Human Anti-PfCSP Recombinant Antibody (clone MGV3)
CAT#: FAMAB-0289WJ
This product is a human monoclonal antibody targets P. falciparum circumsporozoite protein (PfCSP). This antibody has been tested in vitro for their capacity to inhibit PfCSP traversal and invasion of a human hepatocyte cell line. This antibody can be used in applications, such as ELISA, WB, Neut.
Published Data
ELISA
Figure 1 Binding values for the panel of IgG monoclonal antibodies to PfSPZs.
The values indicate the concentration of antibody required to reach a 10,000 MFI.
Tan, J., Sack, B. K., Oyen, D., Zenklusen, I., Piccoli, L., Barbieri, S., Foglierini, M., Fregni, C. S., Marcandalli, J., Jongo, S., Abdulla, S., Perez, L., Corradin, G., Varani, L., Sallusto, F., Sim, B., Hoffman, S. L., Kappe, S., Daubenberger, C., Wilson, I. A., … Lanzavecchia, A. (2018). A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. Nature medicine, 24(4), 401–407.
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Specifications
- Immunogen
- Attenuated Plasmodium falciparum sporozoites (PfCSPs)
- Host Species
- Human
- Type
- Human IgG
- Specificity
- P. falciparum circumsporozoite protein (PfCSP)
- Species Reactivity
- P. falciparum
- Clone
- MGV3
- Applications
- ELISA, WB, Neut
- Related Disease
- P. falciparum infection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- P. falciparum circumsporozoite protein; PfCSP
- UniProt ID
- P02893
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone MGV3"
- CAT
- Product Name
See other products for "PfCSP"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0228-CN | Recombinant Mouse Anti-PfCSP Antibody (2A10) | ELISA, IB, IF, WB | Mouse IgG |
| PABC-471 | Recombinant Human Anti-PfCSP Antibody (MGG4) | ELISA, FC | Human IgG1, κ |
| PABC-491 | Recombinant Human Anti-PfCSP Antibody (mab317) | ELISA, FuncS | Human IgG1, κ |
| VS-0723-CJ13 | Human Anti-PfCSP Recombinant Antibody (clone 663) | ELISA, IF, Inhib, Neut | Human IgG, κ |
| VS-0824-CJ12 | Mouse Anti-PfCSP Recombinant Antibody (clone Ky15.3) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-543 | Human Anti-PfCSP Recombinant Antibody (PABC-543) | ELISA, IF, FuncS | Human IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-306 | Recombinant Human Anti-PfCSP Antibody Fab Fragment (1210) | ELISA | Human Fab |
| PFBC-372 | Human Anti-PfCSP Recombinant Antibody; Fab Fragment (PFBC-372) | ELISA, IF, Inhib | Human Fab |
| PFBC-373 | Human Anti-PfCSP Recombinant Antibody; Fab Fragment (PFBC-373) | ELISA, IF, Inhib | Human Fab |
| PFBC-510 | Recombinant Human Anti-PfCSP Antibody Fab Fragment (PFBC-510) | ELISA, FC | Human Fab |
| PFBC-511 | Recombinant Human Anti-PfCSP Antibody Fab Fragment (mab311) | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-306 | Recombinant Human Anti-PfCSP Antibody scFv Fragment (1210) | ELISA | Human scFv |
| PSBC-372 | Human Anti-PfCSP Recombinant Antibody; scFv Fragment (PSBC-372) | ELISA, IF, Inhib | Human scFv |
| PSBC-373 | Human Anti-PfCSP Recombinant Antibody; scFv Fragment (PSBC-373) | ELISA, IF, Inhib | Human scFv |
| FAMAB-0276WJ-S(P) | Human Anti-PfCSP Recombinant Antibody (clone MGG3); scFv Fragment | ELISA, WB, Neut | Human scFv |
| FAMAB-0278WJ-S(P) | Human Anti-PfCSP Recombinant Antibody (clone MGH2); scFv Fragment | ELISA, WB, Neut | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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