Recombinant Anti-PfRH5 Biparatopic Antibody, Tandem scFv
CAT#: VS-0525-YC145
The Recombinant Anti-PfRH5 Biparatopic Antibody, Tandem scFv is a biparatopic antibody (bpAb) designed to bind two distinct epitopes of PfRH5. This bpAb incorporates tandem scFv arms that simultaneously bind with high affinity to the N-terminus of helix 2 of PfRH5 and the tip of its "kite-like" structure. This latter region directly contacts the N-terminus of helix 4 and each of the three loops linking the converging helices at this apex of PfRH5.
Specifications
- Host Animal 1
- Human
- Host Animal 2
- Human
- Specificity
- PfRH5
- Species Reactivity
- P. falciparum
- Type
- Tandem scFv
- Valency
- 1 + 1
- Epitope 1
- The N terminus of helix 2 of PfRH5
- Epitope 2
- The tip of the "kite-like" structure, contacting the N terminus of helix 4 and each of the three loops that link the converging helices at this apex of PfRH5.
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA, DB
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- Plasmodium falciparum reticulocyte-binding protein homolog 5
Target
- Introduction
- PfRH5 is the leading target for next-generation vaccines against the disease-causing blood-stage of malaria.
- Alternative Names
- Plasmodium falciparum reticulocyte-binding protein homolog 5; RH5; reticulocyte-binding protein homolog 5
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Datasheet
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COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-302 | Recombinant Mouse Anti-PfRH5 Antibody (PABL-302) | WB, BL, FuncS | IgG |
| PABL-679 | Mouse Anti-PfRH5 Recombinant Antibody (PABL-679) | ELISA | Mouse IgG |
| PABJ-0163 | Human Anti-PfRH5 Recombinant Antibody (PABJ-0163) | ELISA, DB, Synergistic effect | Human IgG |
| PABJ-0164 | Human Anti-PfRH5 Recombinant Antibody (PABJ-0164) | ELISA, DB | Human IgG |
| PABJ-0173 | Human Anti-PfRH5 Recombinant Antibody (PABJ-0173) | ELISA, DB, Neut | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-302 | Recombinant Mouse Anti-PfRH5 Antibody scFv Fragment (PSBL-302) | WB, BL, FuncS | scFv |
| PSBL-673 | Mouse Anti-PfRH5 Recombinant Antibody; scFv Fragment (PSBL-673) | ELISA | Mouse scFv |
| PABJ-0163-S(P) | Human Anti-PfRH5 Recombinant Antibody scFv Fragment (PABJ-0163-S(P)) | ELISA, DB, Synergistic effect | Human scFv |
| PABJ-0164-S(P) | Human Anti-PfRH5 Recombinant Antibody scFv Fragment (PABJ-0164-S(P)) | ELISA, DB | Human scFv |
| PABJ-0173-S(P) | Human Anti-PfRH5 Recombinant Antibody scFv Fragment (PABJ-0173-S(P)) | ELISA, DB, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-302 | Recombinant Mouse Anti-PfRH5 Antibody Fab Fragment (PFBL-302) | WB, BL, FuncS | Fab |
| PFBL-673 | Mouse Anti-PfRH5 Recombinant Antibody; Fab Fragment (PFBL-673) | ELISA | Mouse Fab |
| PABJ-0163-F(E) | Human Anti-PfRH5 Recombinant Antibody Fab Fragment (PABJ-0163-F(E)) | ELISA, DB, Synergistic effect | Human Fab |
| PABJ-0164-F(E) | Human Anti-PfRH5 Recombinant Antibody Fab Fragment (PABJ-0164-F(E)) | ELISA, DB | Human Fab |
| PABJ-0173-F(E) | Human Anti-PfRH5 Recombinant Antibody Fab Fragment (PABJ-0173-F(E)) | ELISA, DB, Neut | Human Fab |
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