Mouse Anti-PKHD1 Recombinant Antibody (clone 8G12A1)
CAT#: VS7-0425-WR620
This product is a rat IgG1 antibody that binds to PKHD1. The antibody 8G12A1 recognizes specific amino acid domain of mouse PKHD1 (AA: 3878-4060). It can be used for IHC, ICC, and FC assays. It cross reacts with human.
Specifications
- Immunogen
- Recombinant mouse PKHD1 (AA: 3878-4060) fragment expressed in E. Coli.
- Host Species
- Rat
- Type
- Rat IgG1
- Specificity
- Human PKHD1
- Species Reactivity
- Human
- Clone
- 8G12A1
- Molecule Class
- Transmembrane Protein
- Applications
- IHC, ICC, FC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Immunohistochemistry-Paraffin: 1:200 - 1:1000
Immunocytochemistry: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- FPC; Tigm1
- Gene ID
- 241035
- UniProt ID
- E9PZ36
- Long Name
- PKHD1 ciliary IPT domain containing fibrocystin/polyductin
- Cellular Localization
- Cell membrane; Cell projection; Centromere; Chromosome; Cytoplasm; Cytoskeleton; Endoplasmic reticulum; Golgi apparatus; Membrane; Nucleus; Secreted
- Post Translation Modifications
- Glycoprotein
- Protein Refseq
- NP_694819.2
- Function
- Promotes ciliogenesis in renal epithelial cells and therefore participates in the tubules formation and/or ensures the maintenance of the architecture of the lumen of the kidney (PubMed:18235088, PubMed:20875407).; Has an impact on cellular symmetry by ensuring correct bipolar cell division through the regulation of centrosome duplication and mitotic spindle assembly and by maintaining oriented cell division (OCD) during tubular elongation through planar cell polarity (PCP) pathway (PubMed:19959710).; During epithelial cell morphogenesis regulates also cell-cell and cell-matrix adhesion and participates in cell motility (By similarity).; Promotes cell-cell contact through the positive regulation of PTK2 kinase activity leading to either positive regulation of epithelial cell proliferation through the HRAS/RAF1 pathways, or negative regulation of apoptosis through the PDK1/AKT1 pathway (PubMed:20875407).; May act in collecting-duct and biliary differentiation (By similarity).; May participate in the regulation of the cholangiocytes proliferation and the CCN2 production in an CXCL8-dependent manner (By similarity).
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS7-0425-WR620. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
See other products for "PKHD1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY1261 | Mouse Anti-PKHD1 Recombinant Antibody (clone 10F8D7) | ELISA, IHC, FC, ICC | Mouse IgG1 |
| VS3-XY1262 | Mouse Anti-PKHD1 Recombinant Antibody (clone 5G12G2) | ELISA, FC, ICC, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1661 | Anti-PKHD1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5442 | Anti-Human PKHD1 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: ELISA, IP, FC, FuncS, Neut, IF, IHC
Application: WB, IP, IF, FuncS, FC, Neut, ELISA
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, WB, FC
Application: ELISA, WB
Application: ELISA, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
