Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY277)
CAT#: VS-1225-XY277
It binds Podocalyxin specifically, avoiding cross-reactivity with other glycoproteins. This antibody supports renal and cancer research, suitable for ELISA, WB, and IHC to analyze expression patterns.
Specifications
- Host Animal
- Mouse
- Applications
- WB, IHC, FC, IP
- Specificity
- Podocalyxin
- Target
- Podocalyxin
- Species Reactivity
- Human
- Type
- Mouse IgM
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Affinity chromatography purified
- Format
- Liquid
- Buffer
- PBS, pH 7.2
- Preservative
- 0.09% sodium azide
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- Podocalyxin, a transmembrane sialoglycoprotein of the CD34 family, is predominantly expressed on the apical surface of renal podocytes, where it maintains glomerular filtration barrier integrity via charge repulsion and cytoskeletal interactions. Beyond renal physiology, it is aberrantly upregulated in multiple malignancies, functioning as a key oncogenic factor that promotes cell proliferation, invasion, and metastasis through modulating signaling pathways like PI3K/AKT. Its dual role in normal tissue homeostasis and tumorigenesis renders podocalyxin a promising biomarker and therapeutic target for kidney diseases and cancers.
- Alternative Names
- Podocalyxin
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Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "Podocalyxin"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY276 | Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY276) | WB, IHC, FC, IP | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY278 | Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY278) | WB, IHC, FC, IP | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY279 | Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY279) | WB, IHC, FC, IP | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY280 | Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY280) | WB, IHC, FC, IP | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY281 | Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY281) | WB, IHC, FC, IP | Mouse IgM |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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