Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY280)
CAT#: VS-1225-XY280
This antibody targets Podocalyxin with high selectivity, optimized for compatibility with ELISA, WB, and IHC. It minimizes non-specific binding, ensuring clarity in expression analysis.
Specifications
- Host Animal
- Mouse
- Applications
- WB, IHC, FC, IP
- Specificity
- Podocalyxin
- Target
- Podocalyxin
- Species Reactivity
- Human
- Type
- Mouse IgM
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Affinity chromatography purified
- Format
- Liquid
- Buffer
- PBS, pH 7.2
- Preservative
- 0.09% sodium azide
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- Podocalyxin, a transmembrane sialoglycoprotein of the CD34 family, is predominantly expressed on the apical surface of renal podocytes, where it maintains glomerular filtration barrier integrity via charge repulsion and cytoskeletal interactions. Beyond renal physiology, it is aberrantly upregulated in multiple malignancies, functioning as a key oncogenic factor that promotes cell proliferation, invasion, and metastasis through modulating signaling pathways like PI3K/AKT. Its dual role in normal tissue homeostasis and tumorigenesis renders podocalyxin a promising biomarker and therapeutic target for kidney diseases and cancers.
- Alternative Names
- Podocalyxin
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "Podocalyxin"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY276 | Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY276) | WB, IHC, FC, IP | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY277 | Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY277) | WB, IHC, FC, IP | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY278 | Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY278) | WB, IHC, FC, IP | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY279 | Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY279) | WB, IHC, FC, IP | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY281 | Mouse Anti-Podocalyxin Recombinant Antibody (VS-1225-XY281) | WB, IHC, FC, IP | Mouse IgM |
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