Rabbit Anti-PON1 Recombinant Antibody (clone R07-4I1) (CAT#: VS3-FY1840)

The R07-4I1 recombinant monoclonal antibody is specific for human PON1. It cross-reacts with mouse, rat. It is suitable for use in a variety of assays, including WB, IP. The specificity of the PON1 antibody was confirmed by western blot analysis of PON1 in mouse liver lysates.


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WB

Figure 1 Anti-PON1 Antibody (VS3-FY1840) in WB.

Figure 1 Anti-PON1 Antibody (VS3-FY1840) in WB.

The PON1 expression in mouse liver lysates were detected using the anti-PON1 by western blot assay.


Specifications

  • Immunogen
  • Synthetic peptide of human PON1
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat PON1
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R07-4I1
  • Applications
  • Western Blot, Immunoprecipitation
  • MW
  • The calculated weight of the target protein is approximately 40 kDa, while the observed molecular weight stands at 40 kDa.
  • Related Disease
  • Microvascular Complications Of Diabetes 5 and Amyotrophic Lateral Sclerosis 1

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunoprecipitation: 1/20

Target

  • Alternative Names
  • PON1; ESA; MVCD5; PON; paraoxonase 1
  • Sequence Similarities
  • Belongs to the paraoxonase family.
  • Cellular Localization
  • HDL, Secreted
  • Post Translation Modifications
  • Glycosylated. (P27169-PON1_HUMAN)
    The signal sequence is not cleaved. (P27169-PON1_HUMAN)
    Present in two forms, form B contains a disulfide bond, form A does not. (P27169-PON1_HUMAN)
    Glycosylation at Asn227, Asn253, Asn270, and Asn324 (NX_P27169 [NX_P27169-1])
    Modification sites at PhosphoSitePlus (P27169)
    Glycosylation from GlyConnect PON1_HUMAN (726)
    Glycosylation from GlyGen (P27169) 6 sites, 30 N-linked glycans (3 sites), 1 O-linked glycan (2 sites)
  • Function
  • Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "PON1"

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2788 Hi-Affi™ Recombinant Rabbit Anti-PON1 Monoclonal Antibody (DS2788AB) IHC-P, IP, WB IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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