Mouse Anti-PRKAB2 Recombinant Antibody (clone 7A8C3)

CAT#: VS7-0425-WR685

This product is a mouse IgG2b antibody that binds to human PRKAB2. The antibody 7A8C3 recognizes specific amino acid domain of human PRKAB2 (AA: 1-120). It can be used for FC assay.

Specifications

  • Immunogen
  • Recombinant human PRKAB2 (AA: 1-120) fragment expressed in E. Coli.
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2b
  • Specificity
  • Human PRKAB2
  • Species Reactivity
  • Human
  • Clone
  • 7A8C3
  • Molecule Class
  • Ser/Thr Protein Kinase Family
  • Applications
  • FC
  • Conjugate
  • Unconjugated

Product Property

  • Clonality
  • Monoclonal
  • Purity
  • >95% as determined by SDS-PAGE and SEC-HPLC analysis
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • 0.05% sodium azide
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • Western Blot: 1:500 - 1:2000
    Flow Cytometry: 1:200 - 1:400
    Enzyme-linked Immunosorbent Assay: 1:10000

Target

  • Alternative Names
  • PRKAB2; protein kinase, AMP-activated, beta 2 non-catalytic subunit; 5-AMP-activated protein kinase subunit beta-2; AMPK beta 2; 5 AMP activated protein kinase beta 2 subunit; 5 AMP activated protein kinase subunit beta 2; AMP activated protein kinase beta 2 non catalytic subunit; AMPK beta 2; AMPK beta 2 chain; AMPK subunit beta 2; PRKAB 2; Protein kinase AMP activated beta 2 non catalytic subunit; AMPK beta-2 chain; AMPK subunit beta-2; 5-AMP-activated protein kinase, beta-2 subunit;
  • Long Name
  • Protein Kinase, AMP-Activated, Beta 2 Non-Catalytic Subunit
  • Cellular Localization
  • cytoplasm; cytosol; nucleoplasm; nucleus
  • Post Translation Modifications
  • Phosphoprotein
  • Function
  • Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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Isotype Control

Secondary Antibody

Reconstitution Buffer

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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