Rabbit Anti-PRKCQ Recombinant Antibody (VS13-YC941) (CAT#: VS13-YC941)
The Rabbit Anti-PRKCQ Recombinant Antibody is specific for human PRKCQ. PRKCQ encodes a PKC family member important for T-cell activation, operating phospholipid-dependently and facilitating transcription factor activation. The anti-PRKCQ antibody can be used for Immunohistochemistry (1/100-1/200).
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Custom Production
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Specifications
- Immunogen
- Recombinant human PRKCQ.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human PRKCQ
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
- Related Disease
- Inflammatory Bowel Disease and Gastrointestinal Stromal Tumor
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- PRKCT; nPKC-theta
- Gene ID
- 5588
- UniProt ID
- Q04759
- Long Name
- protein kinase C theta
- Sequence Similarities
- Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
- Cellular Localization
- Cell membrane; Cytoplasm; Membrane
- Protein Refseq
- XP_005252553.1; XP_005252554.1; XP_054222269.1; XP_054222270.1; NP_001229342.1
- Function
- Plays a critical role in TCR/CD28-induced NFATC1 and NFATC2 transactivation by participating in the regulation of reduced inositol 1, 4, 5-trisphosphate generation and intracellular calcium mobilization. After costimulation of T-cells through CD28 can phosphorylate CBLB and is required for the ubiquitination and subsequent degradation of CBLB, which is a prerequisite for the activation of TCR. During T-cells differentiation, plays an important role in the development of T-helper 2 (Th2) cells following immune and inflammatory responses, and, in the development of inflammatory autoimmune diseases, is necessary for the activation of IL17-producing Th17 cells. May play a minor role in Th1 response.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
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Rabbit Monoclonal Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3032z | Mouse Anti-PRKCQ Recombinant Antibody (clone 16G9) | ELISA, WB, FuncS | Mouse IgG1 |
| MOB-2308CT | Recombinant Mouse anti-Human PRKCQ Monoclonal antibody (FQS4905) | WB, ELISA | |
| ZG-0004U | Rabbit Anti-PRKCQ Recombinant Antibody (clone 1B2) | ELISA, WB | Rabbit IgG |
| VS3-FY2064 | Rabbit Anti-PRKCQ Recombinant Antibody (clone R05-5I4) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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