Rabbit Anti-PRPF8 Recombinant Antibody (clone R06-1I7) (CAT#: VS3-FY1857)
This PRPF8 recombinant antibody binds specifically to human PRPF8, a 274 kDa member of the immunodlobulin superfamily. The antibody is recommended for detection of PRPF8 protein by WB, IHC-P. This antbody has been tested by western blot analysis of PRPF8 in Jurkat, Raji lysates.
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WB
Figure 1 Anti-PRPF8 Antibody (VS3-FY1857) in WB.
The PRPF8 expression in Jurkat, Raji lysates were detected using the anti-PRPF8 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human PRPF8
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human PRPF8
- Species Reactivity
- Human
- Clone
- R06-1I7
- Applications
- Western Blot, Immunohistochemistry-Paraffin
- MW
- The calculated weight of the target protein is approximately 274 kDa, while the observed molecular weight stands at 274 kDa.
- Related Disease
- Retinitis Pigmentosa 13 and Retinitis Pigmentosa
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- PRPF8; pre-mRNA processing factor 8; HPRP8; PRP8; PRPC8; RP13; SNRNP220
- Gene ID
- 10594
- UniProt ID
- Q6P2Q9
- Cellular Localization
- Nucleus, Spliceosome
- Post Translation Modifications
- Ubiquitination at Lys36, Lys43, Lys93, Lys218, Lys267, Lys278, Lys301, Lys428, Lys442, Lys452, Lys460, Lys480, Lys525, Lys609, Lys702, Lys705, Lys727, Lys746, Lys785, Lys932, Lys1020, Lys1158, Lys1210, Lys1222, Lys1300, Lys1344, Lys1392, Lys1434, Lys1443, Lys1449, Lys1463, Lys1732, Lys1735, Lys1792, Lys1801, Lys1859, Lys1866, Lys1901, Lys2034, Lys2049, Lys2070, and Lys2140 (NX_Q6P2Q9 [NX_Q6P2Q9-1])
- Protein Refseq
- XP_024306305.1; XP_054170697.1; XP_054185172.1; NP_006436.3
- Function
- Plays a role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as a scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1717CT | Recombinant Mouse anti-Human PRPF8 Monoclonal antibody (3945D2b) | Dot, WB | |
| MRO-1284-CN | Recombinant Rabbit Anti-PRPF8 Monoclonal Antibody (JG57-38) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-WK506 | Rabbit Anti-PRPF8 Recombinant Antibody (clone JG57-38) | WB, ELISA | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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