Mouse Anti-PSME3 Recombinant Antibody (VS7-0425-WR707) (CAT#: VS7-0425-WR707)
This product is a mouse IgG antibody that binds to human PSME3. The antibody can be used for WB, IF, and ICC assays. It cross reacts with mouse, dog, and pig.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Specifications
- Immunogen
- Recombinant human PSME3 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human PSME3
- Species Reactivity
- Human, Mouse, Dog, Pig
- Molecule Class
- 11S Regulator
- Applications
- WB, IF, ICC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Buffer
- 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl)
- Preservative
- 0.2% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:1000 - 1:2000
Immunofluorescence: 1:100 - 1:500
Target
- Alternative Names
- PSME3; PA28-Gamma; 11S Regulator Complex Subunit Gamma; Ki; Ki Antigen; Proteasome (Prosome, Macropain) Activator Subunit 3 (PA28 Gamma; Ki); Proteasome Activator 28 Subunit Gamma; Epididymis Secretory Protein Li 283; Ki Nuclear Autoantigen; 11S Regulator
- Gene ID
- 10197
- UniProt ID
- P61289
- Long Name
- Proteasome Activator Subunit 3
- Cellular Localization
- Cytoplasm; Nucleus; Proteasome
- Post Translation Modifications
- Acetylation; Phosphoprotein
- Protein Refseq
- NP_001253974.1
- Function
- Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition (PubMed:25361978).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "PSME3"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2360z | Mouse Anti-PSME3 Recombinant Antibody (clone 42A1) | WB, IF | Mouse IgG |
MOB-1655CT | Recombinant Mouse anti-Human PSME3 Monoclonal antibody (5C3-D3-H5) | ELISA, WB | |
ZG-0351C | Mouse Anti-PSME3 Recombinant Antibody (ZG-0351C) | WB, IF | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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