Mouse Anti-PTGS2 Recombinant Antibody (clone 4C1H7) (CAT#: VS7-0425-WR709)
This product is a mouse IgG1 antibody that binds to human PTGS2. The antibody 4C1H7 recognizes specific amino acid domain of human PTGS2 (AA: 18-207). It can be used for ICC and FC assays.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1335/990_H3_1_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1335/990_H3_1_selected.jpg
Figure 2 Urinary bladder
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1335/ihc_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1335/ihc_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1335/4023_B_8_5.jpg
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1335/4023_B_8_5.jpg
Figure 4 Seminal vesicle
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1335/4023_A_8_6.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1335/4023_A_8_6.jpg
Figure 5 RNA cell line category: Cell line enriched (BJ hTERT+)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000073756-PTGS2
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000073756-PTGS2
Specifications
- Immunogen
- Recombinant human PTGS2 (AA: 18-207) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human PTGS2
- Species Reactivity
- Human
- Clone
- 4C1H7
- Molecule Class
- Cyclooxygenase-2
- Applications
- ICC, FC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
- Gene ID
- 5743
- UniProt ID
- P35354
- Long Name
- Prostaglandin-endoperoxide synthase 2
- Cellular Localization
- Endoplasmic reticulum; Membrane; Microsome; Nucleus
- Post Translation Modifications
- Acetylation; Disulfide bond; Glycoprotein; S-nitrosylation
- Protein Refseq
- NP_000954.1
- Function
- Dioxygenase; Oxidoreductase; Peroxidase
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Related Resources
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Rabbit Monoclonal Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2922 | Hi-Affi™ Recombinant Rabbit Anti-PTGS2 Monoclonal Antibody (DS2922AB) | IHC-P | IgG |
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For Research Use Only. Not For Clinical Use.
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