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    AbPlus™ Anti-PTPN2 Magnetic Beads (VS-0724-YC212) (CAT#: VS-0724-YC212)

    The AbPlus Anti-PTPN2 Magnetic Beads (VS-0724-YC212) is an innovative affinity resin which is bound with anti-PTPN2 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PTPN2 protein under native and denaturing conditions.

    Specific Inquiry
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/15004/1252_H4_1_selected.jpg
    Normal Tissue
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Glial cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Nuclear
    Neuronal cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Neuropil
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/15004/128829_B_8_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Glandular cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Peripheral nerve/ganglion
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/15004/128829_A_7_3.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in glomeruli
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear
    Cells in tubules
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/15004/128829_A_8_5.jpg
    Figure 5 Lymph node
    Figure 5 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear
    Non-germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/15004/128829_A_8_8.jpg
    RNA Expression
    Figure 6 RNA cell line category: Low cell line specificity
    Figure 6 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000175354-PTPN2/subcellular

    Specifications

    • Applications
    • Immunoprecipitation, Protein Purification
    • Matrix
    • Magnetic bead
    • Bead Ligand
    • Anti-PTPN2 specific antibody
    • Target
    • PTPN2
    • Immunogen
    • Recombinant human PSPH, aa 1-225.
    • Target Species
    • Human
    • Bead Capacity
    • 40 mg/mL
    • Bead size
    • 25 μm
    • Format
    • Suspension
    • Concentration
    • 2 mg/mL
    • Buffer
    • PBS, pH 7.4
    • Preservative
    • 0.1% Sodium azide
    • Storage
    • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

    Applications

    • Application Notes
    • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

    Target

    • Introduction
    • The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome.
    • Alternative Names
    • PSP; PSPHD

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    CAT Product Name Application Type
    MOB-1920MZ Recombinant Mouse Anti-Human PTPN2 Antibody (clone U36-BG4C8) ELISA, WB Mouse antibody
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