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  • Human Anti-PVRIG Recombinant Antibody; Fab Fragment (HPAB-0774LY-F(E))

Human Anti-PVRIG Recombinant Antibody; Fab Fragment (HPAB-0774LY-F(E)) (CAT#: HPAB-0774LY-F(E))

This product is a recombinant human antibody Fab fragment that recognizes PVRIG. The antibody was purified by affinity chromatography.

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  • Conjugation:
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  • Gene Expression
  • Datasheet
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoli & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/1365_E3_2_selected.jpg
Figure 2 IHC staining of human pancreas
Figure 2 IHC staining of human pancreas
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_B_9_5.jpg
Figure 4 Colon
Figure 4 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_A_7_3.jpg
Figure 5 Liver
Figure 5 Liver
(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_A_7_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_A_9_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_A_4_6.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Group enriched (Daudi, JURKAT, MOLT-4, U-698)
Figure 9 RNA cell line category: Group enriched (Daudi, JURKAT, MOLT-4, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000213413-PVRIG/subcellular

Specifications

  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Human Fab
  • Specificity
  • Human PVRIG
  • Species Reactivity
  • Human
  • Applications
  • ELISA, FC, WB, Block

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CD112R; C7orf15

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "PVRIG"

Select a product category from the dropdown menu below to view related products.
Please select product type
ScFv Antibody Products IgG Antibody Products Fab Antibody Products
CAT Product Name Application Type
HPAB-0774LY-S(P) Human Anti-PVRIG Recombinant Antibody; scFv Fragment (HPAB-0774LY-S(P)) ELISA, FC, WB, Block Human scfv
HPAB-0775LY-S(P) Human Anti-PVRIG Recombinant Antibody; scFv Fragment (HPAB-0775LY-S(P)) ELISA, FC, WB, Block Human scfv
HPAB-0776LY-S(P) Human Anti-PVRIG Recombinant Antibody; scFv Fragment (HPAB-0776LY-S(P)) ELISA, FC, WB, Block Human scfv
HPAB-0777LY-S(P) Human Anti-PVRIG Recombinant Antibody; scFv Fragment (HPAB-0777LY-S(P)) ELISA, FC, WB, Block Human scfv
HPAB-0778LY-S(P) Human Anti-PVRIG Recombinant Antibody; scFv Fragment (HPAB-0778LY-S(P)) ELISA, FC, WB, Block Human scfv

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Exceptional Versatility
The Human Anti-PVRIG Fab fragment has become a staple in our lab for its versatility. Its application in ELISA, flow cytometry, and WB has greatly facilitated our research into immune checkpoints. The high purity ensures reliable data, minimizing background noise that we encountered with other antibodies.

Facilitates Detailed Flow Analysis
Our team found this antibody particularly useful for detailed flow cytometry analysis, documenting nuanced changes in immune cell populations. This accuracy is essential for our studies targeting checkpoint regulations.

Promising in Cancer Research
We've observed promising applications for this antibody in deciphering immune checkpoints in melanoma studies. Its precision in targeting and its role in uncovering PVRIG dynamics are shaping the future of our research projects.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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