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    Human Anti-PVRIG Recombinant Antibody; Fab Fragment (HPAB-0774LY-F(E)) (CAT#: HPAB-0774LY-F(E))

    This product is a recombinant human antibody Fab fragment that recognizes PVRIG. The antibody was purified by affinity chromatography.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoli & endoplasmic reticulum.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/1365_E3_2_selected.jpg
    Figure 2 IHC staining of human pancreas
    Figure 2 IHC staining of human pancreas
    (Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/ihc_selected.jpg
    Normal Tissue
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Endothelial cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Glial cells
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Neuropil
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_B_9_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Peripheral nerve/ganglion
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_A_7_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Hepatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_A_7_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in tubules
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_A_9_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Cells in seminiferous ducts
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_A_4_6.jpg
    Figure 8 Lymph node
    Figure 8 Lymph node
    (Non-germinal center cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/47497/106259_A_9_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Group enriched (Daudi, JURKAT, MOLT-4, U-698)
    Figure 9 RNA cell line category: Group enriched (Daudi, JURKAT, MOLT-4, U-698)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000213413-PVRIG/subcellular

    Specifications

    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • Human Fab
    • Specificity
    • Human PVRIG
    • Species Reactivity
    • Human
    • Applications
    • ELISA, FC, WB, Block

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • CD112R; C7orf15

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "PVRIG"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    ScFv Antibody Products IgG Antibody Products Fab Antibody Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    HPAB-0774LY-S(P) Human Anti-PVRIG Recombinant Antibody; scFv Fragment (HPAB-0774LY-S(P)) ELISA, FC, WB, Block Human scfv
    HPAB-0775LY-S(P) Human Anti-PVRIG Recombinant Antibody; scFv Fragment (HPAB-0775LY-S(P)) ELISA, FC, WB, Block Human scfv
    HPAB-0776LY-S(P) Human Anti-PVRIG Recombinant Antibody; scFv Fragment (HPAB-0776LY-S(P)) ELISA, FC, WB, Block Human scfv
    HPAB-0777LY-S(P) Human Anti-PVRIG Recombinant Antibody; scFv Fragment (HPAB-0777LY-S(P)) ELISA, FC, WB, Block Human scfv
    HPAB-0778LY-S(P) Human Anti-PVRIG Recombinant Antibody; scFv Fragment (HPAB-0778LY-S(P)) ELISA, FC, WB, Block Human scfv

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    Exceptional Versatility
    The Human Anti-PVRIG Fab fragment has become a staple in our lab for its versatility. Its application in ELISA, flow cytometry, and WB has greatly facilitated our research into immune checkpoints. The high purity ensures reliable data, minimizing background noise that we encountered with other antibodies.

    Facilitates Detailed Flow Analysis
    Our team found this antibody particularly useful for detailed flow cytometry analysis, documenting nuanced changes in immune cell populations. This accuracy is essential for our studies targeting checkpoint regulations.

    Promising in Cancer Research
    We've observed promising applications for this antibody in deciphering immune checkpoints in melanoma studies. Its precision in targeting and its role in uncovering PVRIG dynamics are shaping the future of our research projects.

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