Rabbit Anti-RAB11A Recombinant Antibody (clone R06-7F2) (CAT#: VS3-XY3484)

It is a recombinant rabbit antibody targeting the RAB11A (RAB11A, member RAS oncogene family), which acts as a major regulator of membrane delivery during cytokinesis. RAB11A may also play a role in melanosome transport and release from melanocytes. The antibody specifically reacts with human, mouse and rat RAB11A. It has been determined using Western Blot and Immunoprecipitation. The recommended dilutions of Western Blot and Immunoprecipitation is 1/500-1/1000 and 1/20, respectively.

Specific Inquiry
  • Size:

  • Conjugation:

  • Endotoxin:

  • Purity:

  • Formats:

  • Isotype Switching:

  • Fc Engineering:

  • Modalities:

Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

Sequences:
Isotype :
Purity :
Endotoxin :
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Conjugation :
Fc Engineering :
Modalities :
Other Requirements:
We require custom production
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat RAB11A
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R06-7F2
  • Applications
  • WB, IP
  • Related Disease
  • Autosomal Dominant Non-Syndromic Intellectual Disability; Primary Microcephaly

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IP: 1/20

Target

  • Alternative Names
  • YL8
  • Long Name
  • RAB11A, member RAS oncogene family
  • Cellular Localization
  • Cell membrane
  • Post Translation Modifications
  • (Microbial infection) Glycosylated on arginine residues by S.typhimurium protein Ssek3. (P62491-RB11A_HUMAN)
    Ubiquitination at Lys179 and Lys207 (NX_P62491 [NX_P62491-1])
    Modification sites at PhosphoSitePlus (P62491)
    Glycosylation from GlyGen (P62491) 1 site, 1 O-linked glycan (1 site)
  • Function
  • The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.
    Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.
    The small Rab GTPase RAB11A regulates endocytic recycling.

Recommended Products

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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