AbPlus™ Anti-RAC1 Magnetic Beads (JF10-11)
CAT#: VS-0424-XY221
The AbPlus Anti-RAC1 Magnetic Beads (JF10-11) is an innovative affinity resin which is bound with anti-RAC1 specific antibody (JF10-11). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of RAC1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35994/265_F2_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35994/ihc_selected.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47820/112664_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Spermatogonia cells Staining: Low Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47820/112664_A_5_6.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47820/112664_A_9_3.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47820/112664_A_9_8.jpg
Normal Tissue
Figure 7 Skin
Keratinocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Melanocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47820/112664_B_9_1.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136238-RAC1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-RAC1 specific antibody (JF10-11)
- Target
- RAC1
- Immunogen
- Recombinant protein
- Target Species
- Human, Mouse, Rat, Zebrafish
- Antibody Clone
- JF10-11
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
- Alternative Names
- MIG5; MRD48; Rac-1; TC-25; p21-Rac1
- Gene ID
- 5879
- UniProt ID
- P63000
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Related Signaling Pathways
Canonical Wnt Signaling Pathway
MAPK Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "RAC1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2124z | Mouse Anti-RAC1 Recombinant Antibody (clone 35A6) | WB, IHC, IP | Mouse IgG2b |
| VS3-QX948 | Mouse Anti-RAC1 Recombinant Antibody (clone 1301CT276.121.104) | WB, IHC, FC | Mouse IgG2b |
| VS3-WK421 | Rabbit Anti-RAC1 Recombinant Antibody (clone JF10-11) | WB, ICC, IF, IP | Rabbit IgG |
| VS3-WK561 | Rabbit Anti-RAC1 Recombinant Antibody (clone JM11-29) | WB, ICC, IF, IHC | Rabbit IgG |
| VS3-FY2857 | Mouse Anti-RAC1 Recombinant Antibody (VS3-FY2857) | WB, IHC, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0486MZ | Chicken Anti-RAC1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2970 | Hi-Affi™ Recombinant Rabbit Anti-RAC1 Monoclonal Antibody (DS2970AB) | ELISA, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1858 | Anti-RAC1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5943 | Anti-Human RAC1 Immunohistochemistry Kit | IHC |
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