Mouse Anti-RGL2 Recombinant Antibody (VS-0326-YC1196)
CAT#: VS-0326-YC1196
This product is an anti-RGL2 antibody panel that contains two antibodies targeting human RGL2. RGL2 is a Guanine Nucleotide Exchange Factor (GEF) that specifically activates the Ral GTPases. It acts as a downstream effector of the Ras signaling pathway. RGL2 signaling coordinates the Ras-mediated regulation of vesicle trafficking and cytokinesis, playing a significant role in promoting tumor cell proliferation and survival. Two monoclonal antibodies, VS-0326-YC71 and VS-0326-YC72, directed against RGL2 were used for in vitro assays including Immunohistochemistry (IHC) and Immunoprecipitation (IP).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47039/1517_B9_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human pancreas
Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/53444/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/53444/124211_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/53444/124211_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/53444/124211_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/53444/124211_A_7_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/53444/124211_A_4_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (HUVEC TERT2, SK-MEL-30, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000237441-RGL2
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| Sub Cat | Type | Clone | Species Reactivity | Applications | Application Notes | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS-0326-YC71 | Mouse IgG2a | RG71 | Human | IP | IP (1/100-1/200) | ||||||
| VS-0326-YC72 | Mouse IgG1 | RG72 | Human | IHC | IHC (1/100-1/200) |
More Infomation
Specifications
- Host Species
- Mouse
- Specificity
- Human RGL2
- Conjugate
- The unconjugated, Biotin and FITC formats are available.
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Target
- Alternative Names
- Ral Guanine Nucleotide Dissociation Stimulator Like 2; Ras-Associated Protein RAB2L; RalGDS-Like Factor; RalGDS-Like 2; RAB2L; Ral Guanine Nucleotide Dissociation Stimulator-Like 2;
- Gene ID
- 5863
- UniProt ID
- O15211
- Long Name
- Ral Guanine Nucleotide Dissociation Stimulator Like 2
- Post Translation Modifications
- Unmodified
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "RGL2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0993MZ | Recombinant Mouse Anti-Human RGL2 Antibody | WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6091 | Anti-RGL2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6092 | Anti-Mouse RGL2 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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