Human Anti-Rotavirus VP8* Recombinant Antibody (clone mAb9); Fab Fragment
CAT#: PABJ-0170-F(E)
This product is a Human antibody Fab fragment that recognizes Rotavirus VP8*. Fab9 binds to a site distant from the HBGA binding site. mAb9 neutralizes the virus is not by blocking the glycan binding.
Specifications
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Rotavirus VP8*
- Species Reactivity
- Rotavirus A
- Clone
- mAb9
- Applications
- ELISA, Neut
Product Property
- Purification
- Purified
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Neutralization.
Target
- Alternative Names
- Rotavirus; VP8*; RV; Rotavirus A
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Successful Viral Neutralization
Our virology lab tested this Fab fragment (clone mAb9) for its ability to neutralize Rotavirus A. Even though it binds distant from the HBGA site, it showed potent neutralization activity in our assays as described. It is a fascinating tool for studying alternative mechanisms of inhibition.
High Quality Recombinant Fab
The purity of this human antibody Fab fragment was verified by SDS-PAGE and HPLC in our lab, confirming the>95% specification. It performed reliably in ELISA to detect the VP8* antigen. The recombinant production ensures that we don't have to worry about the variability of serum.
Q&As
-
Where does this antibody bind on the Rotavirus VP8* antigen?
A: This Human antibody Fab fragment (clone mAb9) binds to a site on Rotavirus VP8* that is distant from the HBGA binding site. It neutralizes the virus through a mechanism other than blocking glycan binding, offering a unique tool for virology research.
-
Is this a full-length antibody or a fragment?
A: This product is a Human Fab fragment, not a full-length IgG. Fab fragments lack the Fc region, which can be advantageous in certain assays to avoid non-specific binding to Fc receptors. It is purified and validated for ELISA and Neutralization.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone mAb9"
- CAT
- Product Name
See other products for "Rotavirus VP8*"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABJ-0170 | Human Anti-Rotavirus VP8* Recombinant Antibody (clone mAb9) | ELISA, Neut | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABJ-0170-S(P) | Human Anti-Rotavirus VP8* Recombinant Antibody (clone mAb9); scFv Fragment | ELISA, Neut | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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