Chicken Anti-RPP30 Recombinant Antibody (clone 5C9); scFv Fragment (CAT#: FAMAB-0006JF-S(P))
Recombinant chicken monoclonal antibody specially binds to human Rpp30. This anti-Rpp30 antibody 5C9 can be potentially wildly used in the treatment of Systemic sclerosis, Raynaud's Phenomenon, systemic lupus erythematosus and poly-myositis.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, nucleoli & microtubule ends.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, nucleoli & microtubule ends.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/if_selected.jpg
Figure 2 IHC staining of human testis
(Immunohistochemical staining of human testis shows moderate nuclear positivity in cells in seminiferous ducts and Leydig cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/ihc_selected.jpg
(Immunohistochemical staining of human testis shows moderate nuclear positivity in cells in seminiferous ducts and Leydig cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/ihc_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/74370_B_9_5.jpg
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/74370_B_9_5.jpg
Figure 4 Colon
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/74370_A_7_3.jpg
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/74370_A_7_3.jpg
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/74370_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/74370_A_8_5.jpg
Figure 6 Testis
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/74370_A_5_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37578/74370_A_5_6.jpg
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148688-RPP30
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148688-RPP30
Specifications
- Immunogen
- Antigen mixture 1 (annexin XI, centromere protein B, DNA topoisomerase I, histidyl tRNA synthetase, Ro60, Rpp38 and U1A) and mixture 2 (a-fodrin, human Pop1 protein, heat shock protein B3, Ro52, Rpp30, Rrp4 and Rrp42)
- Host Species
- Chicken
- Derivation
- Chicken phage display scFv library
- Type
- Chicken scFv
- Specificity
- Human Rpp30
- Species Reactivity
- Human
- Clone
- 5C9
- Applications
- IB, WB, ELISA, FuncS
- Related Disease
- Systemic sclerosis, Raynaud's Phenomenon, Systemic lupus erythematosus, Poly-myositis
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Please select product type
IgG Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3382z | Mouse Anti-RPP30 Recombinant Antibody (clone 39H7) | WB, IP, FuncS | Mouse IgG1 |
| MOB-0806MZ | Recombinant Mouse Anti-Human RPP30 Antibody (clone 3042E6b) | WB | Mouse antibody |
| FAMAB-0006JF | Chicken Anti-RPP30 Recombinant Antibody (clone 5C9) | WB, IF |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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