Rabbit Anti-RPS20 Recombinant Antibody (VS3-FY2864) (CAT#: VS3-FY2864)
The anti-RPS20 antibody is a rabbit recombinant monoclonal antibody that with high affinity for human RPS20 protein. It cross-reacts with mouse, rat, hamster species. This monoclonal antibody proves valuable in disease research related to Diamond-Blackfan Anemia and Familial Colorectal Cancer Type X. The antibody can be utilized for detection of target protein by Western Blot (1/500-1/1000), Immunohistochemistry (1/50-1/100).
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/if_selected.jpg

(Immunohistochemical staining of human oral mucosa shows strong cytoplasmic positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/ihc_selected.jpg

(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_B_8_5.jpg

(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_A_9_3.jpg

(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_A_6_6.jpg

(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_A_8_8.jpg

(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000008988-RPS20
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat and Hamster RPS20
- Species Reactivity
- Human, Mouse, Rat, Hamster
- Applications
- Western Blot, Immunohistochemistry
- Conjugate
- Unconjugated, FITC
- Related Disease
- Diamond-Blackfan Anemia and Familial Colorectal Cancer Type X
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- Ribosomal Protein S20; Small Ribosomal Subunit Protein US10; 40S Ribosomal Protein S20; S20
- Gene ID
- 6224
- UniProt ID
- P60866
- Sequence Similarities
- Belongs to the universal ribosomal protein uS10 family.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Polyubiquitinated by ZNF598 via 'Lys-63'-linked ubiquitin chains when a ribosome has stalled, initiating the ribosome quality control (RQC) pathway to degrade the potentially detrimental aberrant nascent polypeptide (PubMed:28065601, 28132843, 28685749, 32011234, 36302773).
Deubiquitinated by OTUD3 and USP21, antagonizing ZNF598 activity (PubMed:32011234).
(P60866-RS20_HUMAN)
Ufmylated by UFL1. (P60866-RS20_HUMAN)
Ubiquitination at Lys4, Lys30, Lys34, Lys67, and Lys75 (NX_P60866 [NX_P60866-1])
Modification sites at PhosphoSitePlus (P60866)
Glycosylation from GlyGen (P60866) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001139699.1
- Function
- Component of the small ribosomal subunit (PubMed:23636399).
The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "RPS20"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3118 | Hi-Affi™ Recombinant Rabbit Anti-RPS20 Monoclonal Antibody (DS3118AB) | WB, IHC, ICC | IgG |
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For Research Use Only. Not For Clinical Use.
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