Rabbit Anti-RPS20 Recombinant Antibody (VS3-FY2864) (CAT#: VS3-FY2864)
The anti-RPS20 antibody is a rabbit recombinant monoclonal antibody that with high affinity for human RPS20 protein. It cross-reacts with mouse, rat, hamster species. This monoclonal antibody proves valuable in disease research related to Diamond-Blackfan Anemia and Familial Colorectal Cancer Type X. The antibody can be utilized for detection of target protein by Western Blot (1/500-1/1000), Immunohistochemistry (1/50-1/100).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/if_selected.jpg
Figure 2 IHC staining of human oral mucosa
(Immunohistochemical staining of human oral mucosa shows strong cytoplasmic positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/ihc_selected.jpg
(Immunohistochemical staining of human oral mucosa shows strong cytoplasmic positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/ihc_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_B_8_5.jpg
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_B_8_5.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_A_9_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_A_9_3.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_A_6_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_A_6_6.jpg
Figure 6 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_A_8_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3570/10533_A_8_8.jpg
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000008988-RPS20
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000008988-RPS20
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat and Hamster RPS20
- Species Reactivity
- Human, Mouse, Rat, Hamster
- Applications
- Western Blot, Immunohistochemistry
- Conjugate
- Unconjugated, FITC
- Related Disease
- Diamond-Blackfan Anemia and Familial Colorectal Cancer Type X
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- Ribosomal Protein S20; Small Ribosomal Subunit Protein US10; 40S Ribosomal Protein S20; S20
- Gene ID
- 6224
- UniProt ID
- P60866
- Sequence Similarities
- Belongs to the universal ribosomal protein uS10 family.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Polyubiquitinated by ZNF598 via 'Lys-63'-linked ubiquitin chains when a ribosome has stalled, initiating the ribosome quality control (RQC) pathway to degrade the potentially detrimental aberrant nascent polypeptide (PubMed:28065601, 28132843, 28685749, 32011234, 36302773).
Deubiquitinated by OTUD3 and USP21, antagonizing ZNF598 activity (PubMed:32011234).
(P60866-RS20_HUMAN)
Ufmylated by UFL1. (P60866-RS20_HUMAN)
Ubiquitination at Lys4, Lys30, Lys34, Lys67, and Lys75 (NX_P60866 [NX_P60866-1])
Modification sites at PhosphoSitePlus (P60866)
Glycosylation from GlyGen (P60866) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001139699.1
- Function
- Component of the small ribosomal subunit (PubMed:23636399).
The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Please select product type
Rabbit Monoclonal Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3118 | Hi-Affi™ Recombinant Rabbit Anti-RPS20 Monoclonal Antibody (DS3118AB) | WB, IHC, ICC | IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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