Human Anti-RTN4RL2 Recombinant Antibody (P14)
CAT#: HPAB-0739-YJ
This product is a recombinant Chimeric (rabbit/Human) antibody that recognizes Human RTN4RL2. RTN4R It is cross reactive with rat RTN4RL2.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (HMC-1, Karpas-707, REH, RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000186907-RTN4RL2
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Specifications
- Host Species
- Human
- Derivation
- Chimeric (rabbit/Human)
- Type
- Chimeric (rabbit/human) IgG1, κ
- Specificity
- Human
- Species Reactivity
- Human, Rat
- Clone
- P14
- Applications
- ELISA, WB, FC, IF, IP, ICC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Western Blot, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Immunocytochemistry. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
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Versatile in Neurobiology
I recently used the Human Anti-RTN4RL2 Recombinant Antibody (P14) for a research project focusing on nerve regeneration. Its performance was remarkable in identifying receptor interactions, offering precise results in both ELISA and Western Blot assays. The cross-reactivity with rat RTN4RL2 was particularly useful for our study involving animal models. The antibody's high purity and reliability made it an indispensable tool in our laboratory, bringing our exploration of neural pathways to new heights.
Reliable for Complex Assays
As a researcher specializing in cancer biomarkers, the P14 antibody has been incredibly beneficial in our investigations. We employed it in Flow Cytometry and Immunoprecipitation studies to untangle signal transduction pathways in various tumor types. The product's high specificity is unparalleled, minimizing any cross-reactivity with non-target proteins and truly advancing our understanding of disease mechanisms. Storage and handling are straightforward, adding to its convenience.
Essential for Signal Transduction Studies
This antibody is fantastic for detailed signal transduction analysis. We used it extensively in exploring the molecular pathways involved in cell cycle regulation. Its specificity for NgR proteins and robustness across different analytical platforms, including ICC and IF, have enhanced the depth of our research. The antibody is also price-competitive for its quality, making it a valuable addition to any research setting.
Q&As
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What is the primary application of the Human Anti-RTN4RL2 Recombinant Antibody (P14)?
A: This antibody is widely used in various research applications, including ELISA, Western Blotting, Flow Cytometry, Immunofluorescence, Immunoprecipitation, and Immunocytochemistry. Its specific binding to human RTN4RL2 makes it ideal for studying receptor-related proteins in neuroscience and cancer biomarker research.
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What are the key target proteins for this antibody?
A: The antibody targets reticulon-4 receptor-like 2 (RTN4RL2), also known as NgR2, NGRH1, and nogo receptor-like proteins. The specificity for these proteins makes it useful in exploring pathways related to neural growth inhibition and receptor signaling.
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Can this antibody be used for cancer biomarker discovery?
A: Yes, the P14 antibody is applicable in cancer research, aiding the exploration of biomarkers for various cancers, including glioma and liver cancer, by targeting proteins involved in neural and tumor growth regulation.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Clone P14"
- CAT
- Product Name
See other products for "RTN4RL2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0739-YJ-F(E) | Human Anti-RTN4RL2 Recombinant Antibody (P14); Fab Fragment | ELISA, FC, WB, ICC, IF | Chimeric (rabbit/Human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0739-YJ-S(P) | Rabbit Anti-RTN4RL2 Recombinant Antibody (P14); scFv Fragment | ELISA, FC, WB, ICC, IF | Rabbit scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS11-QX127 | Human Anti-RTN4RL2 Recombinant Antibody (clone P14) | ELISA, FC, IP, WB | Human IgG1, κ |
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