Rabbit Anti-SALL4 Antibody (VS-0924-YC89) - Cancer Stem Cell Marker
CAT#: VS-0924-YC89
This product is an anti-SALL4 antibody (VS-0924-YC89) designed to target the human SALL4 protein, a marker for cancer stem cells (CSCs). It is suitable for detecting SALL4 in CSC tissues or cells using Immunohistochemistry (dilution range: 1/50-1/200), Western blot (0.1-0.5 µg/mL), and Immunofluorescence (0.5-2 µg/mL).
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15291/1030_F9_5_red_green.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line SiHa
Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15291/1183_B10_1_red_green.jpg
Normal Tissue
Figure 3 Cerebral cortex
Spermatogonia cells
Staining:High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15291/35651_A_6_6.jpg
Normal Tissue
Figure 4 Ovary
Follicle cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15291/35651_A_5_7.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (AF22, AN3-CA, BEWO, NTERA-2, SiHa, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101115-SALL4
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human SALL4
- Species Reactivity
- Human
- Applications
- IHC, WB, IF
- Related Disease
- Duane-Radial Ray Syndrome and Ivic Syndrome
Product Property
- Clonality
- Polyclonal
- Purification
- Affinity purified using the PrEST antigen as affinity ligand
- Concentration
- 0.1 mg/mL
- Buffer
- PBS, pH 7.2, with 40% glycerol
- Preservative
- 0.02% Sodium azide
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/50-1/200
Western Blot (WB): 0.1-0.5 µg/mL
Immunofluorescence (IF): 0.5-2 µg/mL
Target
- Alternative Names
- Spalt Like Transcription Factor 4; Zinc Finger Protein SALL4; Zinc Finger Protein 797; ZNF797; Sal (Drosophila)-Like 4; Sal-Like 4 (Drosophila); Sal-Like Protein 4; HSAL4; DRRS
- Gene ID
- 57167
- UniProt ID
- Q9UJQ4
- Long Name
- Spalt-like transcription factor 4
- Sequence Similarities
- Belongs to the sal C2H2-type zinc-finger protein family.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Isoform SALL4B exists primarily as a ubiquitinated form. (Q9UJQ4-SALL4_HUMAN)
Sumoylation with both SUMO1 and SUMO2 regulates the stability, subcellular localization, transcriptional activity, and may reduce interaction with POU5F1/OCT4. (Q9UJQ4-SALL4_HUMAN)
Modification sites at PhosphoSitePlus (Q9UJQ4)
Modification sites at neXtProt (NX_Q9UJQ4)
Glycosylation from GlyGen (Q9UJQ4) 3 sites, 1 O-linked glycan (3 sites)
- Protein Refseq
- XP_047296274.1; XP_054179717.1; NP_001304960.1; NP_065169.1
- Function
- Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.
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Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "SALL4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-505 | Recombinant Human Anti-Human SALL4 Antibody Fab Fragment, clone D202 | IP, IF, ELISA | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1200 | Mouse Anti-SALL4 Recombinant Antibody (VS3-WK1200) | WB, IHC | Mouse IgG2b |
| VS3-WK1201 | Mouse Anti-SALL4 Recombinant Antibody (clone ABT-SALL4) | IHC-P, WB | Mouse IgG2b, κ |
| VS3-FY1874 | Rabbit Anti-SALL4 Recombinant Antibody (clone R02-6H7) | WB, IHC-P | Rabbit IgG |
| VS7-0425-WR819 | Mouse Anti-SALL4 Recombinant Antibody (clone 1A3E11) | WB, FC | Mouse IgG1 |
| VS7-0425-WR820 | Mouse Anti-SALL4 Recombinant Antibody (clone 7B6H2) | WB, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6341 | Anti-SALL4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6342 | Anti-Mouse SALL4 Immunohistochemistry Kit | IHC |
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