Human Anti-SARS-CoV-2 N Recombinant Antibody (VS3-CJ1138); scFv Fragment

CAT#: VS3-CJ1138

This product is a human antibody that recognizes SARS-CoV-2 Nucleocapsid protein.

Specifications

  • Host Species
  • Human
  • Type
  • Human scFv
  • Specificity
  • SARS-CoV-2 Nucleocapsid protein single-chain variable fragment
  • Species Reactivity
  • SARS-CoV-2
  • Applications
  • ELISA
  • Conjugate
  • Unconjugated

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Concentration
  • 1 mg/mL (lot specific)
  • Buffer
  • 0.02M PBS, pH 7.4.
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Shipped at 4°C

Applications

  • Application Notes
  • This antibody has been tested for use in ELISA (Use at an assay dependent dilution).

Target

  • Alternative Names
  • GU280_gp10
  • Sequence Similarities
  • Belongs to the betacoronavirus nucleocapsid protein family.
  • Cellular Localization
  • Host cytoplasm, Virion
  • Post Translation Modifications
  • ADP-ribosylated. The ADP-ribosylation is retained in the virion during infection.
    Phosphorylated on serine residues by host GSK3A and GSK3B.
  • Function
  • Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication (By similarity).
    May induce inflammasome responses in cultured cells and mice. Acts by interacting with host NLRP3 to facilitate inflammasome assembly, which induces cytokine release that may play a role in COVID lung injury.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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