Rabbit Anti-SEC61A2 Recombinant Antibody (clone R07-6B6) (CAT#: VS3-FY1877)
The R07-6B6 recombinant monoclonal antibody targets for human SEC61A2 protein, a calculated weight of 52 kDa. It cross-reacts with mouse, rat. The recommend antibody dilution is determined as western blot (dilution 1/500-1/1000), immunohistochemistry (dilution 1/50-1/100), immunofluorescence (dilution 1/50-1/200), immunoprecipitation (dilution 1/20).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Immunogen
- Recombinant human SEC61A protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat SEC61A2
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R07-6B6
- Applications
- Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunofluorescence, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 52 kDa, while the observed molecular weight stands at 40 kDa.
- Related Disease
- Autosomal Dominant Severe Congenital Neutropenia
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunofluorescence: 1/50-1/200
Immunoprecipitation: 1/20
Target
- Alternative Names
- Sec61 Translocon Alpha 2 Subunit; Sec61 Alpha 2 Subunit (S. Cerevisiae); Sec61 Alpha-2
- Gene ID
- 55176
- UniProt ID
- Q9H9S3
- Sequence Similarities
- Belongs to the SecY/SEC61-alpha family.
- Cellular Localization
- Endoplasmic reticulum, Membrane
- Post Translation Modifications
- Ubiquitination at Lys4 (NX_Q9H9S3 [NX_Q9H9S3-1])
Modification sites at PhosphoSitePlus (Q9H9S3)
- Protein Refseq
- NP_001136099.1; NP_001136100.1; NP_060614.2
- Function
- Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
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