AbPlus™ Anti-SEMA4A Magnetic Beads (VS-0724-YC1282)
CAT#: VS-0724-YC1282
The AbPlus Anti-SEMA4A Magnetic Beads (VS-0724-YC1282) is an innovative affinity resin which is bound with anti-SEMA4A specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of SEMA4A protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows strong membranous positivity in a subset of non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_4_8_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_B_8_5.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_4_6.jpg
Normal Tissue
Figure 5 Lymph node
Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_8_8.jpg
Normal Tissue
Figure 6 Tonsil
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69136/152135_A_4_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196189-SEMA4A
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-SEMA4A specific antibody
- Target
- SEMA4A
- Immunogen
- Recombinant human Semaphorin 4A/SEMA4A/Semaphorin B, aa 1-683.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]
- Alternative Names
- Semaphorin 4A; Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) And Short Cytoplasmic Domain, (Semaphorin) 4A; Semaphorin-B; Sema B; SEMAB; SEMB; Semaphorin-4A; CORD10; RP35;
- Gene ID
- 64218
- UniProt ID
- Q9H3S1
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SEMA4A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-422CT | Anti-Human SEMA4A Recombinant Antibody (HuLB51) | WB, ELISA, FC | Humanized antibody |
| TAB-423CT | Anti-Human SEMA4A Recombinant Antibody (HuLB70) | WB, ELISA, FC | Humanized antibody |
| TAB-422CT-S(P) | Anti-Human SEMA4A Recombinant Antibody scFv Fragment (HuLB51) | WB, ELISA, FC | Humanized antibody |
| TAB-423CT-S(P) | Anti-Human SEMA4A Recombinant Antibody scFv Fragment (HuLB70) | WB, ELISA, FC | Humanized antibody |
| TAB-422CT-F(E) | Anti-Human SEMA4A Recombinant Antibody Fab Fragment (HuLB51) | WB, ELISA, FC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-424CT | Anti-Human SEMA4A Recombinant Antibody (126-28-1) | ELISA, FC, IHC, BL | |
| TAB-425CT | Anti-Human SEMA4A Recombinant Antibody (161-51-1) | ELISA, FC, BL | |
| TAB-426CT | Anti-Human SEMA4A Recombinant Antibody (161-70-1 ) | ELISA, FC, IHC, BL | |
| TAB-427CT | Anti-Human SEMA4A Recombinant Antibody (161-15B-1) | ELISA, FC, BL | |
| TAB-428CT | Anti-Human SEMA4A Recombinant Antibody (161-90) | ELISA, FC, BL |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1941CQ | Recombinant Rat Anti-Sema4a Antibody (CBL203) | FC, Neut | IgG1 |
| NEUT-1942CQ | Recombinant Rat Anti-Sema4a Antibody (CBL647) | FC, CyTOF, Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC155 | Recombinant Anti-SEMA4A Vesicular Antibody, EV Displayed (VS-0425-YC155) | Block, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6443 | Anti-SEMA4A Immunohistochemistry Kit | IHC |
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