Mouse Anti-SRMS Recombinant Antibody (clone 2506W61)
CAT#: VS-0625-FY87
The Mouse IgG1 kappa monoclonal antibody, clone 2506W61, is highly reactive with Human, Mouse, and Rat SRMS. It was generated by targeting amino acids 1-143 of human SRMS. With an observed antigen size of about 37 kDa (calculated 51.58 kDa), this antibody is suitable for a wide range of applications including Western Blot, Immunoprecipitation, Immunofluorescence, Immunohistochemistry (Paraffin), and ELISA.
Specifications
- Immunogen
- Antibody raised against human SRMS, targeting amino acids 1-143 at the N-terminus.
- Host Species
- Mouse
- Type
- Mouse IgG1, kappa
- Species Reactivity
- Human, Mouse, Rat
- Clone
- 2506W61
- Applications
- Western Blot, Immunoprecipitation, Immunofluorescence, Immunohistochemistry-Paraffin, ELISA
- Related Disease
- Bone Osteosarcoma
Product Property
- Purification
- Purified with Protein A or G affinity chromatography
- Purity
- >90% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Optimal dilutions for assays should be determined by the user.
Target
- Alternative Names
- Src-Related Kinase Lacking C-Terminal Regulatory Tyrosine And N-Terminal Myristylation Sites; EC 2.7.10.2; C20orf148; Chromosome 20 Open Reading Frame 148; Tyrosine-Protein Kinase Srms; DJ697K14.1; EC 2.7.10; PTK70; SRM
- Gene ID
- 6725
- UniProt ID
- Q9H3Y6
- Long Name
- Src-Related Kinase Lacking C-Terminal Regulatory Tyrosine And N-Terminal Myristylation Sites
- Sequence Similarities
- Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Modification sites at PhosphoSitePlus
Modification sites at neXtProt
- Protein Refseq
- XP_054179893.1; NP_543013.1
- Function
- Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues (PubMed:23822091).
Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues (PubMed:29496907).
Phosphorylation of KHDRBS1 is EGF-dependent (PubMed:29496907).
Phosphorylates OTUB1, promoting deubiquitination of RPTOR.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
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