Rabbit Anti-SRP19 Recombinant Antibody (clone R58-1O-7)
CAT#: VS3-FY2160
This R58-1O-7 recombinant monoclonal antibody that has a high affinity for human SRP19 protein, a calculated weight of 16 kDa. It cross-reacts with mouse, rat.
The following recommendations serve as a starting point for assay optimization. The actual working concentration may vary and should be determined by the user. The R58-1O-7 is recommended for detection of target protein by western blotting (dilution range 1:500-1:1000), immunohistochemistry (dilution range 1:100-1:200), immunofluorescence (dilution range 1:50-1:200).
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat SRP19
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R58-1O-7
- Applications
- Western Blot, Immunohistochemistry-Paraffin, Immunofluorescence
- Conjugate
- Unconjugated
- MW
- The calculated weight of the target protein is approximately 16kDa, while the observed molecular weight stands at 20kDa.
- Related Disease
- Shwachman-Diamond Syndrome 1 and Severe Congenital Neutropenia
Product Property
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4), 150 mM NaCl, 50% glycerol
- Preservative
- 0.02% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/100-1/200
Immunofluorescence: 1/50-1/200
Target
- Alternative Names
- Signal Recognition Particle 19; Signal Recognition Particle 19kDa
- Gene ID
- 6728
- UniProt ID
- P09132
- Sequence Similarities
- Belongs to the SRP19 family.
- Cellular Localization
- Cytoplasm, Nucleus, Signal recognition particle
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P09132)
Modification sites at neXtProt (NX_P09132)
Glycosylation from GlyGen (P09132) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001191122.1; NP_001191123.1; NP_001191125.1; NP_001191128.1; NP_003126.1
- Function
- Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).
Binds directly to 7SL RNA (By similarity).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "SRP19"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6898 | Anti-SRP19 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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