Rabbit Anti-STOML2 Recombinant Antibody (clone R09-6C3)
CAT#: VS3-FY1618
The R09-6C3 recombinant monoclonal antibody has a high affinity for human STOML2. It cross-reacts with mouse, rat. It is suitable for use in a variety of assays, including WB, ICC/IF, IP. This SLP2 antibody was verified by western blot analysis of SLP2 in K562, rat brain, C6, 3T3, Hela lysates.
Tested Data
WB
Figure 1 Anti-STOML2 Antibody (VS3-FY1618) in WB.
The SLP2 expression in K562, rat Brain, C6, 3T3, Hela lysates were detected using the anti-STOML2/SLP2 by western blot assay.
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Specifications
- Immunogen
- Synthetic peptide of human STOML2
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat STOML2
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R09-6C3
- Applications
- Western Blot, Immunofluorescence, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 39 kDa, while the observed molecular weight stands at 39 kDa.
- Related Disease
- Macroglobulinemia and Monoclonal Gammopathy Of Uncertain Significance
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunofluorescence: 1/50-1/200
Immunoprecipitation: 1/20
Target
- Alternative Names
- SLP-2; HSPC108
- Gene ID
- 30968
- UniProt ID
- Q9UJZ1
- Sequence Similarities
- Belongs to the band 7/mec-2 family.
- Cellular Localization
- Cell membrane, Cytoplasm, Cytoskeleton, Membrane, Mitochondrion, Mitochondrion inner membrane
- Post Translation Modifications
- Hyperphosphorylated at Ser-17 in some patients with monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma (MM) and Waldenstrom macroglobulinemia due to impaired dephosphorylation by PP2A.
- Protein Refseq
- NP_001273960.1; NP_001273961.1; NP_001273962.1; NP_038470.1
- Function
- Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "STOML2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0541MZ | Chicken Anti-SLP-2 (ab1) Polyclonal IgY | WB | Chicken antibody |
| BRD-0542MZ | Chicken Anti-SLP-2 (ab2) Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6993 | Anti-STOML2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6994 | Anti-Mouse STOML2 Immunohistochemistry Kit | IHC |
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