Mouse Anti-SULT1A1 Recombinant Antibody (VS3-FY2885) (CAT#: VS3-FY2885)
This mouse anti-SULT1A1 recombinant monoclonal antibody is specifically binding to human, mouse, rat SULT1A1 protein. The calculated molecular weight of the protein is about 34.2 kDa. The monoclonal antibody can be used in the area of Mandibulofacial Dysostosis With Alopecia and Acetaminophen Metabolism. The antibody can be utilized for detection of SULT1A1 by Western Blot (1/500-1/2000).
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51051/113945_A_4_2_selected.jpg
(Immunohistochemical staining of human small intestine shows cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51051/113945_A_4_2_selected.jpg
Figure 2 Small intestine
(Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49500/113939_A_5_2.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49500/113939_A_5_2.jpg
Figure 3 Colon
(Enterocytes
Staining: Low
Intensity: Weak
Quantity:>75%
Enterocytes - Microvilli
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51051/113945_A_7_3.jpg
(Enterocytes
Staining: Low
Intensity: Weak
Quantity:>75%
Enterocytes - Microvilli
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51051/113945_A_7_3.jpg
Figure 4 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51051/113945_A_7_4.jpg
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51051/113945_A_7_4.jpg
Figure 5 Kidney
(Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51051/113945_A_9_5.jpg
(Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51051/113945_A_9_5.jpg
Figure 6 RNA cell line category: Group enriched (EFO-21, Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196502-SULT1A1/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196502-SULT1A1/subcellular
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human, Mouse and Rat SULT1A1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- Western Blot
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 34.2 kDa.
- Related Disease
- Mandibulofacial Dysostosis With Alopecia and Acetaminophen Metabolism
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Target
- Alternative Names
- Sulfotransferase 1A1, ST1A1, 2.8.2.1, Aryl sulfotransferase 1, HAST1/HAST2, Phenol sulfotransferase 1, Phenol-sulfating phenol sulfotransferase 1, P-PST 1, ST1A3, Thermostable phenol sulfotransferase, Ts-PST, SULT1A1, STP, STP1
- Gene ID
- 6817
- UniProt ID
- P50225
- Sequence Similarities
- Belongs to the sulfotransferase 1 family.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P50225)
Modification sites at neXtProt
- Protein Refseq
- XP_016879094.1; XP_016879097.1; XP_016879099.1; XP_047290500.1
- Function
- Plays an important role in the sulfonation of endogenous molecules such as steroid hormones and 3,3'-diiodothyronin (PubMed:16221673, 12471039, 22069470, 21723874, 10199779, 7834621).
Mediates the sulfate conjugation of a variety of xenobiotics, including the drugs acetaminophen and minoxidil (By similarity).
Mediates also the metabolic activation of carcinogenic N-hydroxyarylamines leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2931z | Mouse Anti-SULT1A1 Recombinant Antibody (MOB-2931z) | FC, IF, IHC, WB | Mouse IgG1 |
| MOB-1977CT | Recombinant Mouse anti-Human SULT1A1 Monoclonal antibody (EML1976) | WB |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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