Mouse Anti-SUZ12 Monoclonal Antibody (clone 2C11) (CAT#: VS7-0425-WR935)
This product is a mouse IgG1 antibody that binds to human SUZ12. The antibody 2C11 can be used for ICC assay.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEK 293
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoli & nuclear bodies.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/1043_A4_1_selected.jpg
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoli & nuclear bodies.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/1043_A4_1_selected.jpg
Figure 2 IHC staining of human appendix
(Immunohistochemical staining of human appendix shows nuclear positivity in lymphoid tissue and glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_1_2_selected.jpg
(Immunohistochemical staining of human appendix shows nuclear positivity in lymphoid tissue and glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_1_2_selected.jpg
Figure 3 Colon
(Glandular cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_7_3.jpg
(Glandular cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_7_3.jpg
Figure 4 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_7_5.jpg
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_7_5.jpg
Figure 5 Lymph node
(Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_9_8.jpg
(Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_9_8.jpg
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000178691-SUZ12/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000178691-SUZ12/subcellular
Specifications
- Immunogen
- Recombinant human SUZ12 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human SUZ12
- Species Reactivity
- Human
- Clone
- 2C11
- Molecule Class
- Polycomb Repressive Complex 2 Subunit
- Applications
- ICC
- Conjugate
- Unconjugated
- Related Disease
- Imagawa-Matsumoto syndrome (IMMAS)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:50
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- SUZ12; CHET9; JJAZ1; KIAA0160; Polycomb protein SUZ12; Chromatin precipitated E2F target 9 protein; ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homolog
- Gene ID
- 23512
- UniProt ID
- Q15022
- Long Name
- SUZ12 polycomb repressive complex 2 subunit
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Isopeptide bond; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_001308136.1
- Function
- Chromatin regulator; Repressor
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1974MZ | Recombinant Mouse Anti-Human SUZ12 Antibody | ELISA, IHC-P, WB | Mouse antibody |
| MRO-1460-CN | Recombinant Rabbit Anti-SUZ12 Monoclonal Antibody (CBACN-542) | WB, IF, IP | Rabbit IgG |
| MRO-2205-CN | Rabbit Anti-SUZ12 Polyclonal Antibody (MRO-2205-CN) | WB | Rabbit IgG |
| VS3-FY1416 | Recombinant Rabbit Anti-SUZ12 Antibody (clone R07-6C3) | WB, IP | Rabbit IgG |
| VS13-YC1131 | Rabbit Anti-SUZ12 Recombinant Antibody (VS13-YC1131) | WB, ICC, IF, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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