Mouse Anti-SYT1 Monoclonal Antibody (VS7-0425-WR945)
CAT#: VS7-0425-WR945
This product is a mouse IgG antibody that binds to human SYT1. The antibody can be used for WB and ELISA assays.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8394/142559_B_8_5.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (hTERT-HME1, hTERT-RPE1, LHCN-M2, SH-SY5Y, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000067715-SYT1/subcellular
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Specifications
- Immunogen
- Recombinant human SYT1 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human SYT1
- Species Reactivity
- Human
- Molecule Class
- Molecular Class A Synaptotagmin Protein
- Applications
- WB, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Baker-Gordon syndrome (BAGOS)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- SYT1; Synaptotagmin I; Synaptotagmin 1; P65; SYT; SVP65; Synaptotagmin-1; SytI
- Gene ID
- 6857
- UniProt ID
- P21579
- Long Name
- Synaptotagmin 1
- Cellular Localization
- Cytoplasm; Cytoplasmic vesicle; Membrane; Synapse
- Post Translation Modifications
- Glycoprotein; Lipoprotein; Palmitate; Phosphoprotein
- Protein Refseq
- NP_001129277.1
- Function
- Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity).; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity).; It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "SYT1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1973MZ | Recombinant Mouse Anti-Rat SYT1 Antibody (clone BTW40) | ICC, IF, WB | Mouse antibody |
| VS-0223-WK72 | Rabbit Anti-SYT1 Recombinant Antibody (VS-0223-WK72) | WB, IP, ICC, IHC, IHC-P | Rabbit IgG |
| VS-0223-WK73 | Rabbit Anti-SYT1 Recombinant Antibody (VS-0223-WK73) | WB, IP, IHC | Rabbit IgG |
| VS-0223-WK74 | Rabbit Anti-SYT1 Recombinant Antibody (VS-0223-WK74) | ICC | Rabbit IgG |
| VS-0223-WK75 | Guinea pig Anti-SYT1 Recombinant Antibody (VS-0223-WK75) | WB, ICC, IHC, IHC-P | Guinea pig IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0732MZ | Chicken Anti-SYT1 Polyclonal IgY | ICC, IF, IHC, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2237 | Anti-SYT1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7057 | Anti-Rat SYT1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC58 | Recombinant Anti-SYT1 Vesicular Antibody, EV Displayed (VS-0425-YC58) | ELISA, FC, Cell-uptake |
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