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SYT1

Anti-SYT1 Products

Guinea pig Anti-SYT1 Recombinant Antibody (VS-0223-WK75) (VS-0223-WK75)
- Derivation: Guinea pig
- Species Reactivity: Rat, Mouse, Human, Zebrafish
- Type: Guinea pig IgG
- Application: WB, ICC, IHC, IHC-P
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Rabbit Anti-SYT1 Recombinant Antibody (VS-0223-WK74) (VS-0223-WK74)
- Derivation: Rabbit
- Species Reactivity: Rat
- Type: Rabbit IgG
- Application: ICC
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Recombinant Mouse Anti-Rat SYT1 Antibody (clone BTW40) (MOB-1973MZ)
- Species Reactivity: Rat
- Type: Mouse antibody
- Application: ICC/IF, WB
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Mouse Anti-SYT1 Recombinant Antibody (clone 14H2) (MOB-3883z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: ELISA, IHC, WB
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Rabbit Anti-SYT1 Recombinant Antibody (VS-0223-WK73) (VS-0223-WK73)
- Derivation: Rabbit
- Species Reactivity: Rat
- Type: Rabbit IgG
- Application: WB, IP, IHC
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Rabbit Anti-SYT1 Recombinant Antibody (VS-0223-WK72) (VS-0223-WK72)
- Derivation: Rabbit
- Species Reactivity: Rat, Mouse, Human, Zebrafish
- Type: Rabbit IgG
- Application: WB, IP, ICC, IHC, IHC-P
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Mouse Anti-SYT1 Recombinant Antibody (clone 8G11B10) (VS3-QX1080)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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Recombinant Anti-SYT1 Vesicular Antibody, EV Displayed (VS-0425-YC58) (VS-0425-YC58)
- Species Reactivity: Human, Rat, Mouse, Zebrafish
- Target: SYT1
- Host Animal: Rabbit
- Application: ELISA, FC, Cell-uptake
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Anti-SYT1 Immunohistochemistry Kit (VS-0325-XY2237)
- Species Reactivity: Human, Mouse, Rat
- Target: SYT1
- Application: IHC
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Anti-Rat SYT1 Immunohistochemistry Kit (VS-0525-XY7057)
- Species Reactivity: Rat
- Target: SYT1
- Application: IHC
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Chicken Anti-SYT1 Polyclonal IgY (BRD-0732MZ)
- Species Reactivity: Human, Rat, Mouse
- Type: Chicken antibody
- Application: ICC/IF, IHC, WB
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Mouse Anti-SYT1 Monoclonal Antibody (VS7-0425-WR945) (VS7-0425-WR945)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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Anti-SYT1 (clone W24V129) Recombinant Antibody Coupled Liposome (VS-1024-FY131) (VS-1024-FY131)
- Antibody Host: Mouse
- Antibody Reactivity: Human
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For Research Use Only. Not For Clinical Use.

This gene encodes a member of the synaptotagmin protein family. The synaptotagmins are integral membrane proteins of synaptic vesicles that serve as calcium sensors in the process of vesicular trafficking and exocytosis. The encoded protein participates in triggering neurotransmitter release at the synapse in response to calcium binding. Mutations in this gene are associated with Baker-Gordon syndrome.

Protein class

Disease related genes, Human disease related genes, Potential drug targets, Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Excitatory neurons, Inhibitory neurons, Bipolar cells, Rod photoreceptor cells, Cone photoreceptor cells)

Immune cell specificity

Immune cell enhanced (naive B-cell, memory B-cell)

Cell line specificity

Cell line enhanced (hTERT-HME1, hTERT-RPE1, LHCN-M2, SH-SY5Y, WM-115)

Interaction

Homotetramer (Probable). Interacts with SCAMP5 (PubMed:19234194). Interacts with STON2 (PubMed:11381094). Forms a complex with SV2B, syntaxin 1 and SNAP25 (By similarity). Interacts with SV2A, SV2B and SV2C (By similarity). Interacts with RIMS1 (By similarity). Interacts with PRRT2 (By similarity). Interacts with DNAJC5 in a phosphorylation-dependent manner (By similarity). Interacts (via N-terminus) with RAB3A (By similarity). Interacts with SYT12 (By similarity). Interacts with calmodulin (By similarity).

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