CytoStream™ Rabbit Anti-TAB1 Recombinant Antibody (VS13-YC1135)
CAT#: VS13-YC1135
The CytoStream™ Rabbit Anti-TAB1 Recombinant Antibody is specific for human, mouse and rat TAB1. TAB1 encodes a regulator of MAP kinase pathways like MAP3K7/TAK1 activation, with TGF beta-mediated pathway interactions and alternative transcript isoforms. The anti-TAB1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39988/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nuclear speckles & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32328/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/57104/134615_A_4_1_selected.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39988/93682_A_4_6.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39988/93682_A_9_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39988/93682_A_7_5.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100324-TAB1
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Specifications
- Immunogen
- Recombinant human TAB1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat TAB1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, ICC, IF, IP, FC
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunofluorescence (IF): 1/50-1/200
Immunoprecipitation (IP): 1/40
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 1; TAK1-Binding Protein 1; Mitogen-Activated Protein Kinase Kinase Kinase 7 Interacting Protein 1; Mitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 1; MAP3K7IP1; Transforming Growth Factor Beta-Activated Kinase-Binding Protein 1;
- Gene ID
- 10454
- UniProt ID
- Q15750
- Long Name
- TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 1
- Function
- Signal transduction
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Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "TAB1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3869z | Mouse Anti-TAB1 Recombinant Antibody (clone 18B5) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| ZG-128R | Mouse Anti-TAB1 Recombinant Antibody (ZG-128R) | WB | Mouse IgG |
| ZG-129R | Mouse Anti-TAB1 Recombinant Antibody (ZG-129R) | WB | Mouse IgG |
| VS3-QX1081 | Mouse Anti-TAB1 Recombinant Antibody (clone 1B9-D11-B10) | WB | Mouse IgG2b |
| VS3-XY1482 | Mouse Anti-TAB1 Recombinant Antibody (clone 1G2) | WB, IP, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3486 | Hi-Affi™ Recombinant Rabbit Anti-TAB1 Monoclonal Antibody (DS3486AB) | IHC-P, WB, IP, ICC, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY498 | Rabbit Anti-NHP TAB1 Recombinant Antibody (VS-1024-XY498) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7063 | Anti-TAB1 Immunohistochemistry Kit | IHC |
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