Rabbit Anti-TFAP2A Recombinant Antibody (clone R07-7E5)
CAT#: VS3-FY1651
This incredible rabbit recombinant monoclonal antibody that is purified by affinity chromatography. It has been meticulously designed to target human and rat TFAP2A. The calculated molecular weight of the antigen is 48 kDa; the observed molecular weight of the protein is 48 kDa.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/56871/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/326/if_selected.jpg
Normal Tissue
Figure 3 Placenta
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/56871/170334_A_1_7_val_selected.jpg
Normal Tissue
Figure 4 Kidney
Collecting ducts Staining: Medium Intensity: Strong Quantity: <25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/326/170388_A_7_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HDLM-2, hTCEpi, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000137203-TFAP2A
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Specifications
- Immunogen
- Synthetic peptide of human AP2 alpha
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat TFAP2A
- Species Reactivity
- Human, Rat
- Clone
- R07-7E5
- Applications
- Western Blot, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 48 kDa, while the observed molecular weight stands at 48 kDa.
- Related Disease
- Branchiooculofacial Syndrome and Amblyopia
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- Transcription Factor AP-2 Alpha; Transcription Factor AP-2 Alpha (Activating Enhancer Binding Protein 2 Alpha); Activating Enhancer-Binding Protein 2-Alpha; AP-2 Transcription Factor; Activator Protein 2; AP2-ALPHA; AP2TF
- Gene ID
- 7020
- UniProt ID
- P05549
- Sequence Similarities
- Belongs to the AP-2 family.
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Sumoylated on Lys-10; which inhibits transcriptional activity.
- Protein Refseq
- NP_001027451.1; NP_001035890.1; NP_001358995.1
- Function
- Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "TFAP2A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0625MZ | Recombinant Mouse Anti-Human TFAP2A Antibody (clone B7/3/3) | ELISA, IHC-P, WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3537 | Rabbit Anti-TFAP2A Recombinant Antibody (clone DS3537AB) | WB, IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX1110 | Mouse Anti-TFAP2A Recombinant Antibody (clone 3C1-H7-G9) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX1111 | Mouse Anti-TFAP2A Recombinant Antibody (clone 4C11) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX1112 | Mouse Anti-TFAP2A Recombinant Antibody (clone 10-C5) | WB, ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY1501 | Mouse Anti-TFAP2A Recombinant Antibody (clone 4A9D6) | ELISA, WB, IHC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY28 | Rabbit Anti-NHP TFAP2A Recombinant Antibody (VS-1024-XY28) | WB, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2270 | Anti-TFAP2A Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7182 | Anti-Mouse TFAP2A Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7181 | Anti-Human TFAP2A Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7183 | Anti-Rat TFAP2A Immunohistochemistry Kit | IHC |
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