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TFAP2A
Anti-TFAP2A Recombinant Antibody Products
- Mouse Anti-TFAP2A Recombinant Antibody (clone 4A9D6) (VS3-XY1501)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC, FC
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- Mouse Anti-TFAP2A Recombinant Antibody (clone 10-C5) (VS3-QX1112)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ICC, FC
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- Mouse Anti-TFAP2A Recombinant Antibody (clone 4C11) (VS3-QX1111)
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Monkey, Rat
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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- Rabbit Anti-NHP TFAP2A Recombinant Antibody (VS-1024-XY28) (VS-1024-XY28)
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- Species Reactivity: Human, Mouse, Non-human primate, Rat
- Type: Rabbit IgG
- Application: WB, IF
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- Anti-TFAP2A Immunohistochemistry Kit (VS-0325-XY2270)
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- Species Reactivity: Human, Mouse, Rat
- Target: TFAP2A
- Application: IHC
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- Mouse Anti-TFAP2A Recombinant Antibody (clone 1A10C5) (VS7-0425-WR969)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ICC, FC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC, ICC, IP
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- Mouse Anti-TFAP2A Recombinant Antibody (clone 7D2B5) (VS7-0425-WR968)
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- Species Reactivity: Human, Mouse, Monkey, Rat
- Type: Mouse IgG1
- Application: IHC, FC
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- Mouse Anti-TFAP2A Recombinant Antibody (clone 2H9F12) (VS7-0425-WR967)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: WB, FC
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- Mouse Anti-TFAP2A Recombinant Antibody (clone 2H9B5) (VS7-0425-WR966)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ICC, FC
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- Rabbit Anti-TFAP2A Recombinant Antibody (VS13-YC1150) (VS13-YC1150)
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IP
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.
Protein class
Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Cytotrophoblasts, Extravillous trophoblasts, Basal squamous epithelial cells, Squamous epithelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HDLM-2, hTCEpi, SuSa)
Interaction
Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members. Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I. Interacts with RALBP1 in a complex also containing EPN1 and NUMB during interphase and mitosis. Interacts with KCTD1; this interaction represses transcription activation. Interacts (via C-terminus) with CITED2 (via C-terminus); the interaction stimulates TFAP2A-transcriptional activation. Interacts (via N-terminus) with EP300 (via N-terminus); the interaction requires CITED2. Interacts with KCTD15; this interaction inhibits TFAP2A transcriptional activation.
Molecular function
Activator, DNA-binding
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