Mouse Anti-TG Recombinant Antibody (VS3-CJ249) (CAT#: VS3-CJ249)
This product is a mouse antibody that recognizes TG.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Thyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77/306_B_1_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77/306_B_1_5.jpg
Figure 2 RNA cell line category: Cell line enhanced (HDLM-2, HSkMC, Karpas-707, PC-3, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000042832-TG
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000042832-TG
Figure 2 RNA cell line category: Cell line enhanced (HDLM-2, HSkMC, Karpas-707, PC-3, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000042832-TG
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000042832-TG
Specifications
- Immunogen
- KLH-conjugated synthetic peptide encompassing a sequence within human Thyroglobulin
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human TG
- Species Reactivity
- Human
- Applications
- IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Immunogen affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.2% BSA, PBS.
- Preservative
- 0.01% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Immunohistochemistry (1:100-1:300).
Target
- Alternative Names
- Thyroglobulin; TGN; AITD3
- Gene ID
- 7038
- UniProt ID
- P01266
- Sequence Similarities
- Belongs to the type-B carboxylesterase/lipase family.
- Cellular Localization
- Secreted
- Protein Refseq
- NP_003226.4
- Function
- Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (PubMed:32025030, PubMed:17532758).
The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen (PubMed:32025030).
Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (PubMed:32025030).
One dimer produces 7 thyroid hormone molecules (PubMed:32025030).
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TG"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2326MZ | Recombinant Mouse Anti-Human TG Antibody (clone Uh 332) | ICC, IHC-Fr, IHC-P | Mouse antibody |
| FAMAB-0320CQ | Mouse Anti-TG Recombinant Antibody (clone 2F6F2) | ELISA | Mouse IgG1, κ |
| FAMAB-0321CQ | Mouse Anti-TG Recombinant Antibody (clone 3B8G9) | ELISA | Mouse IgG2a, κ |
| ZG-0118C | Mouse Anti-TG Recombinant Antibody (clone ABT-TG) | IHC-P, IF | Mouse IgG |
| ZG-0119C | Mouse Anti-TG Recombinant Antibody (clone PT2174) | IHC-P, IF | Mouse IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0285-YC-S(P) | Mouse Anti-TG Recombinant Antibody (clone Tg10); scFv Fragment | ELISA, WB | Mouse scFv |
| FAMAB-0320CQ-S(P) | Mouse Anti-TG Recombinant Antibody (clone 2F6F2); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0321CQ-S(P) | Mouse Anti-TG Recombinant Antibody (clone 3B8G9); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0322CQ-S(P) | Mouse Anti-TG Recombinant Antibody (clone 4D11 F4); scFv Fragment | ELISA | Mouse scFv |
| HPAB-J0238-YC-S(P) | Mouse Anti-TG Recombinant Antibody (clone Tg-60); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0320CQ-F(E) | Mouse Anti-TG Recombinant Antibody (clone 2F6F2); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0321CQ-F(E) | Mouse Anti-TG Recombinant Antibody (clone 3B8G9); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0322CQ-F(E) | Mouse Anti-TG Recombinant Antibody (clone 4D11 F4); Fab Fragment | ELISA | Mouse Fab |
| HPAB-J0238-YC-F(E) | Mouse Anti-TG Recombinant Antibody (clone Tg-60); Fab Fragment | ELISA | Mouse Fab |
| HPAB-J0239-YC-F(E) | Human Anti-TG Recombinant Antibody (clone hTg-37); Fab Fragment | WB, FC | Humanized (mouse/human) Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-A1244-YJ | Human Anti-TG Recombinant Antibody (HPAB-A1244-YJ) | ELISA | Human VH |
| HPAB-A1245-YJ | Human Anti-TG Recombinant Antibody (HPAB-A1245-YJ) | ELISA, DB, IHC, IF, SPR | Human VH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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