AbPlus™ Anti-TSG101 Magnetic Beads (VS-0724-YC611) (CAT#: VS-0724-YC611)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-TSG101 specific antibody

• Target
• TSG101

• Immunogen
• Synthetic peptide corresponding to the N-terminus of the human TSG101.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]

• Alternative Names
• Tumor Susceptibility 101; ESCRT-I Complex Subunit TSG101; Tumor Susceptibility Gene 101; Tumor Susceptibility Gene 10; Tumor Susceptibility Gene 101 Protein; Tumor Susceptibility Protein; VPS23; TSG10;

• Gene ID
• 7251

• UniProt ID
• Q99816

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