Mouse Anti-TTC3 Recombinant Antibody (TT519)

CAT#: VS-0326-YC519

The anti-TTC3 recombinant antibody (TT519) reacts with human TTC3. TTC3 is an E3 ubiquitin ligase whose gene is located in the Down Syndrome Critical Region on chromosome 21. It ubiquitinates and promotes the degradation of Akt. TTC3 signaling acts as a negative regulator of neuronal proliferation and neurite outgrowth; its overexpression contributes to the cognitive defects in Down syndrome. The anti-TTC3 antibody (TT519) has been tested in Immunohistochemistry (IHC).

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Human TTC3
  • Species Reactivity
  • Human
  • Clone
  • TT519
  • Applications
  • IHC
  • Conjugate
  • The unconjugated, Biotin and FITC formats are available.

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Affinity purified
  • Format
  • Liquid
  • Buffer
  • PBS
  • Preservative
  • 0.05% Sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Applications

  • Application Notes
  • IHC (1/20-1/100)

Target

  • Alternative Names
  • Tetratricopeptide Repeat Domain 3; RING-Type E3 Ubiquitin Transferase TTC3; Tetratricopeptide Repeat Protein 3; RING Finger Protein 105; TPR Repeat Protein 3; TPR Repeat Protein D; RNF105;
  • Long Name
  • Tetratricopeptide Repeat Domain 3
  • Post Translation Modifications
  • Unmodified
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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