Mouse Anti-USP2 Recombinant Antibody (VS3-FY2914) (CAT#: VS3-FY2914)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human and African Green Monkey USP2

• Species Reactivity
• Human, African Green Monkey

• Applications
• Western Blot

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 68.7 kDa.

• Related Disease
• Fasciitis and Azoospermia

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/2000

• Alternative Names
• Ubiquitin Specific Peptidase 2; Ubiquitin-Specific-Processing Protease 2; 41 KDa Ubiquitin-Specific Protease; Deubiquitinating Enzyme 2; Ubiquitin Thioesterase 2; UBP41; Ubiquitin Carboxyl-Terminal Hydrolase 2

• Gene ID
• 9099

• UniProt ID
• O75604

• Sequence Similarities
• Belongs to the peptidase C19 family. USP2 subfamily.

• Cellular Localization
• Cytoplasm
  Cytoplasm, perinuclear region

• Post Translation Modifications
• Modification sites at PhosphoSitePlus (O75604)
  Modification sites at neXtProt (NX_O75604)
  Glycosylation from GlyGen (O75604) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• XP_005271779.1; XP_016874028.1; XP_054226438.1; XP_054226439.1

• Function
• Plays a role in the G1/S cell-cycle progression in normal and cancer cells (PubMed:19917254).
  Regulates the circadian clock by modulating its intrinsic circadian rhythm and its capacity to respond to external cues (By similarity).
  Associates with clock proteins and deubiquitinates core clock component PER1 but does not affect its overall stability (By similarity).
  Regulates the nucleocytoplasmic shuttling and nuclear retention of PER1 and its repressive role on the clock transcription factors CLOCK and BMAL1 (By similarity).
  Plays a role in the regulation of myogenic differentiation of embryonic muscle cells (By similarity).

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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