Human Anti-αvβ3 Integrin Recombinant Antibody (clone LM609) (CAT#: HPAB-1305WJ)
This product is a human antibody targeting human αvβ3. This antibody can be used for the treatment of integrin mediated diseases.
Specific Inquiry
ELISA
Figure 1 Linear regression plots for the number of adherent SS RBC/100 μm2 according to the venular diameter in preparations treated with LM609 (or IgG) and PAF.
Kaul, D. K., Tsai, H. M., Liu, X. D., Nakada, M. T., Nagel, R. L., & Coller, B. S. (2000). Monoclonal antibodies to αVβ3 (7E3 and LM609) inhibit sickle red blood cell–endothelium interactions induced by platelet-activating factor: Presented in part at the INSERM Symposium, Paris, France, September 2, 1995 (ref 24), and at the 40th Annual Meeting of the American Society of Hematology, Miami, FL, December 7, 1998. Blood, The Journal of the American Society of Hematology, 95(2), 368-374.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human αvβ3
- Species Reactivity
- Human
- Clone
- LM609
- Applications
- ELISA
- Related Disease
- Integrin mediated diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The αvβ3 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- ΑVβ3; Alpha-v beta-3; alphaV/beta3 integrin
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone LM609"
See other products for "αVβ3 integrin"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-705 | Anti-αvβ3 Integrin Recombinant Antibody (Etaracizumab/Etaratuzumab/Medi-522) | FC, IP, ELISA, Neut, FuncS, IF, IHC | IgG2 - kappa |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-705 | Afuco™ Anti-αVβ3 Integrin ADCC Recombinant Antibody (Etaracizumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1305WJ-S(P) | Human Anti-αvβ3 Integrin Recombinant Antibody (clone LM609); scFv Fragment | ELISA | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1305WJ-F(E) | Human Anti-αvβ3 Integrin Recombinant Antibody (clone LM609); Fab Fragment | ELISA | Humanized Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-A1325-YJ | Mouse Anti-αvβ3 Integrin Recombinant Antibody (clone D12) | ELISA, Inhib, FC | Mouse IgG1 |
| HPAB-A1326-YJ | Human Anti-αvβ3 Integrin Recombinant Antibody (clone chD12) | ELISA, Inhib, FC | Chimeric (mouse/human) IgG1 |
| HPAB-A1327-YJ | Human Anti-αvβ3 Integrin Recombinant Antibody (clone huD12) | ELISA, Inhib, FC | Humanized IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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