Anti-αvβ3 Integrin Recombinant Antibody (TAB-705) (CAT#: TAB-705)
Recombinant humanized (from mouse) antibody expressed in CHO binding to human αVβ3 integrin. It is a humanized monoclonal antibody which is being investigated for the treatment of metastatic melanoma, prostate cancer, ovarian cancer and various other types of cancer.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
SDS-PAGE
Figure 1 Anti-Human IAV HA Recombinant Antibody (TAB-705)-Fc silenced in SDS-PAGE
SDS-PAGE analysis of TAB-705, Fc silenced, in non-reduced (lane 2) and β-mercaptoethanol-reduced (lane 1) conditions.
SEC-HPLC
Figure 2 Anti-Human IAV HA Recombinant Antibody (TAB-705)-Fc silenced in SEC-HPLC
The purity of TAB-705, Fc silenced, was greater than 99% as determined by SEC-HPLC.
WB
Figure 3 Anti-Human IAV HA Recombinant Antibody (TAB-705)-Fc silenced in WB
Western blot analysis of TAB-705, Fc silenced, was performed by loading αvβ3 Integrin Protein, Human.
ELISA
Figure 4 Anti-Human IAV HA Recombinant Antibody (TAB-705)-Fc silenced in ELISA
ELISA analysis of TAB-705, Fc silenced, was performed by coating with αvβ3 Integrin Protein, Human.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG2 - kappa
- Species Reactivity
- Human
- Applications
- FC, IP, ELISA, Neut, FuncS, IF, IHC
- MW
- 144.3 kDa
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Applications
- Application Notes
- The αVβ3 integrin antibody has been reported in applications of FC, IP, ELISA, Neut, FuncS, IF, IHC.
Target
- Alternative Names
- etaracizumab/etaratuzumab/MEDI-522;abegrin;892553-42-3;Etaratuzumab;MEDI-522;Abegrin;αVβ3
Related Resources
Please refer to Etaracizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Etaracizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ADCC Enhanced Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-705 | Afuco™ Anti-αVβ3 Integrin ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-705) | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
Customer Reviews and Q&As
Customer Review
Q&As
Great Specificity
The specificity of Etaracizumab towards αvβ3 integrin is outstanding. It has minimized cross-reactivity issues we encountered with other antibodies, leading to more accurate results.
Great for Flow Cytometry
Etaracizumab worked exceptionally well in our flow cytometry assays. It helped us accurately quantify αvβ3 integrin on different cell types, aiding our cellular analysis projects.
Reliable Conjugation
We conjugated Etaracizumab with Alexa Fluor and achieved clear, bright staining in our imaging studies. It's a reliable option for those needing fluorescent labeling for visualization.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-705, RRID: AB_3111984)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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