Rat Anti-WDR12 Recombinant Antibody (WD954)

CAT#: VS-0326-YC954

The anti-WDR12 recombinant antibody (WD954) reacts with human WDR12. WDR12 is a component of the PeBoW complex (PES1-BOP1-WDR12), which is essential for the processing of 28S and 5.8S ribosomal RNAs. WDR12 signaling coordinates ribosome biogenesis with the cell cycle; its disruption triggers a p53-mediated nucleolar stress response, leading to growth arrest and apoptosis in highly proliferative cells. The anti-WDR12 antibody (WD954) has been tested in Immunocytochemistry (ICC), Immunofluorescence (IF) and Western Blot (WB).

Specifications

  • Host Species
  • Rat
  • Type
  • Rat IgG
  • Specificity
  • Human WDR12
  • Species Reactivity
  • Human
  • Clone
  • WD954
  • Applications
  • ICC, IF, WB
  • Conjugate
  • The unconjugated, Biotin and FITC formats are available.

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Affinity purified
  • Format
  • Liquid
  • Buffer
  • 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 40% Glycerol and 0.05% Protective protein.
  • Preservative
  • 0.01% Sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Applications

  • Application Notes
  • WB (1/500-1/2000), ICC/IF (1/100-1/200)

Target

  • Alternative Names
  • WD Repeat Domain 12; WD Repeat-Containing Protein 12; Ribosome Biogenesis Protein WDR12; YTM1;
  • Long Name
  • WD Repeat Domain 12
  • Post Translation Modifications
  • Unmodified
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Secondary Antibody

See other products for "WDR12"

Select a product category from the dropdown menu below to view related products.

CAT Product Name Application Type
VS-0724-YC433 AbPlus™ Anti-WDR12 Magnetic Beads (VS-0724-YC433) IP, Protein Purification
CAT Product Name Application Type
VS-0625-FY1483 Human Anti-WDR12 Recombinant Antibody (clone 2506W1378) ELISA, Spiked IP, IF Human IgG1
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