Rabbit Anti-WNT16 Recombinant Antibody (clone R08-2G2) (CAT#: VS3-FY1938)

• Immunogen
• Synthetic peptide of human Wnt16

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse and Rat WNT16

• Species Reactivity
• Human, Mouse, Rat

• Clone
• R08-2G2

• Applications
• Western Blot, Immunoprecipitation

• MW
• The calculated weight of the target protein is approximately 41 kDa, while the observed molecular weight stands at 41 kDa.

• Related Disease
• Osteoporosis-Pseudoglioma Syndrome and Mullerian Aplasia And Hyperandrogenism

• Purification
• Affinity Purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000
  Immunoprecipitation: 1/20

• Alternative Names
• Wnt Family Member 16; Wingless-Type MMTV Integration Site Family, Member 16

• Gene ID
• 51384

• UniProt ID
• Q9UBV4

• Sequence Similarities
• Belongs to the Wnt family.

• Cellular Localization
• Extracellular matrix, Secreted

• Post Translation Modifications
• Palmitoleoylation is required for efficient binding to frizzled receptors.
  Depalmitoleoylation leads to Wnt signaling pathway inhibition.
  (Q9UBV4-WNT16_HUMAN)
  Glycosylation at Asn143, Asn189, and Asn311 (NX_Q9UBV4 [NX_Q9UBV4-1])
  Modification sites at PhosphoSitePlus (Q9UBV4)
  Glycosylation from GlyGen (Q9UBV4) 4 sites, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_057171.2; NP_476509.1

• Function
• Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-054CQ
• Goat Anti-Rabbit IgG Antibody, R-PE

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-055CQ
• Chicken Anti-Rabbit IgG (H&L) Antibody

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