Rabbit Anti-ZEB1 Recombinant Antibody (VS13-YC1239)
CAT#: VS13-YC1239
The Rabbit Anti-ZEB1 Recombinant Antibody is specific for human ZEB1. ZEB1 is a transcription factor repressing certain genes and involved in corneal dystrophy and other conditions. The anti-ZEB1 antibody can be used for Immunohistochemistry (1/100-1/200).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27524/if_selected.jpg
Subcellular Location
Figure 2 IHC staining of human smooth muscle
Immunohistochemical staining of human smooth muscle shows strong nuclear positivity in smooth muscle cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79943/170691_B_6_7_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27524/218_C10_1_red_green.jpg
Subcellular Location
Figure 4 IF staining of human cell line A549
Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79943/2000_B6_1_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Glial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_B_9_5.jpg
Normal Tissue
Figure 6 Colon
Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_A_9_3.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_A_8_5.jpg
Normal Tissue
Figure 8 Testis
Peritubular cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_A_6_6.jpg
Normal Tissue
Figure 9 Smooth muscle
Smooth muscle cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_B_6_7.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (ASC TERT1, TIME)
Cell lines ordered by descending RNA expression order.
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (ASC TERT1, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000148516-ZEB1
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Specifications
- Immunogen
- Recombinant human AREB6.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human ZEB1
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
- Related Disease
- Corneal Dystrophy, Fuchs Endothelial; Corneal Dystrophy, Posterior Polymorphous
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.1) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- Zinc Finger E-Box Binding Homeobox 1; Transcription Factor 8 (Represses Interleukin 2 Expression); Posterior Polymorphous Corneal Dystrophy 3; Negative Regulator Of IL2; AREB6; TCF8; Zinc Finger Homeodomain Enhancer-Binding Protein; Delta-Crystallin Enhancer Binding Factor 1; Zinc Finger E-Box-Binding Homeobox 1; NIL-2-A Zinc Finger Protein;Transcription Factor 8; DELTAEF1; ZFHX1A; FECD6; NIL2A; ZFHEP; PPCD3; TCF-8; BZP;
- Gene ID
- 6935
- UniProt ID
- P37275
- Long Name
- Zinc Finger E-Box Binding Homeobox 1
- Cellular Localization
- Nucleus
- Protein Refseq
- XP_047281639.1
- Function
- Acts as a transcriptional repressor.
Inhibits interleukin-2 (IL-2) gene expression.
Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "ZEB1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-693 | Human Anti-ZEB1 Recombinant Antibody (clone U20) | IP, IF, ELISA | Human IgG |
| MOB-0682MZ | Recombinant Mouse Anti-Human ZEB1 Antibody (clone 527B8I20) | WB | Mouse antibody |
| MOB-120LC | Mouse Anti-ZEB1 Recombinant Antibody (clone 2A8A6) | WB, FC | Mouse IgG |
| VS3-XY1617 | Mouse Anti-ZEB1 Recombinant Antibody (clone 2A8H3) | ELISA, WB, IHC, FC, ICC | Mouse IgG1 |
| VS3-XY3543 | Rabbit Anti-ZEB1 Recombinant Antibody (clone R01-5A7) | WB, IHC-P, ICC, IF, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY8008 | Anti-ZEB1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY8009 | Anti-Mouse ZEB1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY8010 | Anti-Canine ZEB1 Immunohistochemistry Kit | IHC |
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