Rabbit Anti-ZEB1 Recombinant Antibody (clone H-102) (CAT#: VS3-CJ921)
This product is a rabbit antibody that recognizes human, mouse, and rat ZEB1.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27524/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27524/if_selected.jpg
Figure 2 IHC staining of human smooth muscle
(Immunohistochemical staining of human smooth muscle shows strong nuclear positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79943/170691_B_6_7_selected.jpg
(Immunohistochemical staining of human smooth muscle shows strong nuclear positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79943/170691_B_6_7_selected.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27524/218_C10_1_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27524/218_C10_1_red_green.jpg
Figure 4 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79943/2000_B6_1_red_green.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79943/2000_B6_1_red_green.jpg
Figure 5 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Glial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_B_9_5.jpg
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Glial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_B_9_5.jpg
Figure 6 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_A_9_3.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_A_9_3.jpg
Figure 7 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_A_8_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_A_8_5.jpg
Figure 8 Testis
(Peritubular cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_A_6_6.jpg
(Peritubular cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_A_6_6.jpg
Figure 9 Smooth muscle
(Smooth muscle cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_B_6_7.jpg
(Smooth muscle cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58686/125920_B_6_7.jpg
Figure 10 RNA cell line category: Cell line enhanced (ASC TERT1, TIME)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000148516-ZEB1
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000148516-ZEB1
Figure 10 RNA cell line category: Cell line enhanced (ASC TERT1, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000148516-ZEB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000148516-ZEB1
Specifications
- Immunogen
- Amino acids 39-140 of ZEB1 of human origin
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat ZEB1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- H-102
- Applications
- WB, IF, IP
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunofluorescence, Immunoprecipitation.
Target
- Alternative Names
- BZP; TCF8; AREB6; FECD6; NIL2A; PPCD3; ZFHEP; ZFHX1A; DELTAEF1
- Gene ID
- 6935
- UniProt ID
- P37275
- Sequence Similarities
- Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
- Cellular Localization
- Nucleus
- Protein Refseq
- NP_001121600.1; NP_001167564.1; NP_001167565.1
- Function
- Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-693 | Human Anti-ZEB1 Recombinant Antibody (clone U20) | IP, IF, ELISA | Human IgG |
| MOB-0682MZ | Recombinant Mouse Anti-Human ZEB1 Antibody (clone 527B8I20) | WB | Mouse antibody |
| MOB-120LC | Mouse Anti-ZEB1 Recombinant Antibody (clone 2A8A6) | WB, FC | Mouse IgG |
| VS3-XY1617 | Mouse Anti-ZEB1 Recombinant Antibody (clone 2A8H3) | ELISA, WB, IHC, FC, ICC | Mouse IgG1 |
| VS13-YC1239 | Rabbit Anti-ZEB1 Recombinant Antibody (VS13-YC1239) | IHC-P | Rabbit IgG |
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