Rabbit Anti-ZIC1 Recombinant Antibody (clone R09-4A6)

CAT#: VS3-XY3544

The recombinant rabbit antibody reacts with ZIC1 (Zic family member 1), which plays important roles in the early stage of organogenesis of the CNS. ZIC1 also involves in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). This antibody specifically reacts with human, mouse and rat ZIC1. It has been tested using Western Blot, Flow cytometry, Immunocytochemistry or Immunofluorescence.

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat ZIC1
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R09-4A6
  • Applications
  • WB, ICC, IF, FC
  • Related Disease
  • Craniosynostosis 6; Structural Brain Anomalies With Impaired Intellectual Development

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IF: 1/50-1/200
    FC: 1/50-1/100

Target

  • Alternative Names
  • ZIC; CRS6; BAIDCS; ZNF201
  • Long Name
  • Zic family member 1
  • Cellular Localization
  • Nucleus, Cytoplasm
  • Post Translation Modifications
  • Modification sites at PhosphoSitePlus (Q15915)
    Modification sites at neXtProt (NX_Q15915)
  • Function
  • Acts as a transcriptional activator.
    Involved in neurogenesis.
    Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum.
    Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN).
    Plays a role in the regulation of MF axon pathway choice.
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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Isotype Control

Recommended Dilution Buffer

Secondary Antibody

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MOR-3921 Rabbit Anti-ZIC1 Recombinant Antibody (clone DS3921AB) WB, ICC, FC Rabbit IgG
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