Rat Anti-ZP2 Recombinant Antibody (clone IE3) (CAT#: FAMAB-0137-CN)

The rat mAb IE3 is a monoclonal antibody that binds the amino terminus of mouse ZP2, a critical ligand for taxon-specific sperm binding.


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IHC

Figure 1 PAS-stained section of ovary of 7-month-old AAV-IE3 female.

Figure 1 PAS-stained section of ovary of 7-month-old AAV-IE3 female.

Ovaries from infertile females expressing IE3 for 6 months appeared histologically normal, and contained follicles at multiple stages of development, as well as multiple corpora lutea.

Li, J., Olvera, A. I., Akbari, O. S., Moradian, A., Sweredoski, M. J., Hess, S., & Hay, B. A. (2015). Vectored antibody gene delivery mediates long-term contraception. Current Biology, 25(19), R820-R822.


Specifications

  • Immunogen
  • Purified mouse zonae pellucidae
  • Host Species
  • Rat
  • Type
  • Rat IgG2a
  • Specificity
  • Mouse ZP2
  • Species Reactivity
  • Mouse
  • Clone
  • IE3
  • Applications
  • WB, ELISA, IF, IP

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Zp-2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone IE3"

See other products for "ZP2"

Recombinant Antibody

CAT Product Name Application Type
MOB-2462z Mouse Anti-ZP2 Recombinant Antibody (clone 31B6) WB, ELISA, IF, IP Mouse IgG1, κ
VS3-FY1576 Recombinant Mouse Anti-ZP2 Antibody (clone 2F11E4) ELISA, IHC, FC Mouse IgG1

scFv Fragment Antibody

CAT Product Name Application Type
FAMAB-0137-CN-S(P) Rat Anti-ZP2 Recombinant Antibody (clone IE3); scFv Fragment WB, ELISA, IF, IP Rat scFv

Fab Fragment Antibody

CAT Product Name Application Type
FAMAB-0137-CN-F(E) Rat Anti-ZP2 Recombinant Antibody (clone IE3); Fab Fragment WB, ELISA, IF, IP Rat Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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