APC-DRB1*04:04/Human MART-1 (RNGYRALMDKSLHVGTQCALTRR) MHC Tetramer (CAT#: MHC-YF1568)

• Allele
• DRB1*04:04

• Class
• Class II

• MHC Species
• Human

• Antigen
• MART-1

• Antigen Species
• Human

• Peptide
• RNGYRALMDKSLHVGTQCALTRR

• Range
• 51-73

• Conjugate
• APC

• Application
• FCM

• Antigen Introduction
• Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the MLANA o "MALENA" gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.

• Alternative Names
• MLANA; melan-A; MART1; MART-1

• Gene ID
• 2315

• UniProt ID
• Q16655

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