FITC-DRB1*04:04/Human MART-1 (RNGYRALMDKSLHVGTQCALTRR) MHC Tetramer
CAT#: MHC-YF1577
This product is a MHC tetramer of biotinylated peptide/MHC complex composed MART-1-derived peptide of RNGYRALMDKSLHVGTQCALTRR sequence covering 51-73 and DRB1*04:04 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specifications
- Allele
- DRB1*04:04
- Class
- Class II
- MHC Species
- Human
- Antigen
- MART-1
- Antigen Species
- Human
- Peptide
- RNGYRALMDKSLHVGTQCALTRR
- Range
- 51-73
- Conjugate
- FITC
- Application
- FCM
Target
- Antigen Introduction
- Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the MLANA o "MALENA" gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.
- Alternative Names
- MLANA; melan-A; MART1; MART-1
- Gene ID
- 2315
- UniProt ID
- Q16655
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