BV421-DRB1*04:01/Human MART-1 (RNGYRALMDKSLHVGTQCALTRR) MHC Tetramer (CAT#: MHC-YF1583)
This product is a MHC tetramer of biotinylated peptide/MHC complex composed MART-1-derived peptide of RNGYRALMDKSLHVGTQCALTRR sequence covering 51-73 and DRB1*04:01 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Specifications
- Allele
- DRB1*04:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- MART-1
- Antigen Species
- Human
- Peptide
- RNGYRALMDKSLHVGTQCALTRR
- Range
- 51-73
- Conjugate
- BV421
- Application
- FCM
Target
- Antigen Introduction
- Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the MLANA o "MALENA" gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.
- Alternative Names
- MLANA; melan-A; MART1; MART-1
- Gene ID
- 2315
- UniProt ID
- Q16655
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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